Advances in Immunology - 1st Edition - ISBN: 9780123737083, 9780080553702

Advances in Immunology, Volume 95

1st Edition

Editors: Frederick Alt
eBook ISBN: 9780080553702
Hardcover ISBN: 9780123737083
Imprint: Academic Press
Published Date: 1st October 2007
Page Count: 282
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Table of Contents

Fate Decisions Regulating Bone Marrow and Peripheral B Lymphocyte Development Tolerance and Autoimmunity: Lessons at the bed-side of Primary Immunodeficiencies B cell self-tolerance in humans Manipulation of regulatory T-cell number and function with CD28-specific monoclonal antibodies Osteoimmunology: a view from the bone Mast Cell Proteases


Description

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.

Readership

Immunologists and infectious disease specialists, cell biologists and hematologists


Details

No. of pages:
282
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080553702
Hardcover ISBN:
9780123737083

Ratings and Reviews


About the Editors

Frederick Alt Editor

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA