CD22: A Multi-Functional Receptor that RegulatesB Lymphocyte Survival and Signal Transduction Tetramer analysis of human autoreactive CD4 positive T cells Regulation of Phospholipase C-ƒ×2 networks in B lymphocytes Role of Human Mast Cells and Basophils in Bronchial Asthma A novel recognition system for MHC class I molecules constituted by PIR Dendric Cell Biology The Murine Diabetogenic Class II Histocompatibility Molecule I-Ag7: Structural and Functional Properties and Specificity of Peptide Selection RNAi and RNA-based regulartionof immune system function
Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
- Now Available Online as part of the Life Sciences package via ScienceDirect
- Highly respected review series with an impact factor in 2003 of 7.424 and ranked number 8/114
Immunologists, infectious disease specialists, cell biologists and hematologists
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- © Academic Press 2005
- 27th September 2005
- Academic Press
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Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA
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