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Advances in Immunology - 1st Edition - ISBN: 9780120224814, 9780080548302

Advances in Immunology, Volume 81

1st Edition

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Serial Editor: Frederick Alt
Hardcover ISBN: 9780120224814
eBook ISBN: 9780080548302
Imprint: Academic Press
Published Date: 18th December 2003
Page Count: 388
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Table of Contents

Preface Frederick W. Alt Regulation of the immune response by the 'interaction of chemokines and proteases Molecular mechanisms of host-pathogen interaction: Entry and survival of mycobacteria in macrophages B Lymphoid Neoplasms of Mice: Charac'teristics of Naturally Occurring and Engineered Diseases and Relationships to Human disorders Prions and the immune system: a journey through gut spleen, and nerves Roles of the Semaphorin Family in immune regulation HLA-G molecules: from maternal-fetal tolerance to tissue acceptance The Zebrafish as a model organism to study development of the immune system Control of autoimmunity by naturally arising regulatory CD4+ T cells


Volume 81 of Advances in Immunology contains articles on a vast range of immunology topics including the regulation of the immune response by the interaction of chemokines and proteases as well as roles of the Semaphorin Family in immune regulation. It has a chapter devoted to B Lymphoid Neoplasms of Mice and another on the Zebrafish as a model organism to study development of the immune system. This volume will be of interest to immunologists in all industries.

Key Features

  • Edited by a new editor, Frederick W. Alt
  • Covers molecular mechanisms of host-pathogen interaction
  • Discusses prions and the immune system


Researchers in immunology, cell and molecular biology, virology, and medicine.


No. of pages:
© Academic Press 2003
18th December 2003
Academic Press
Hardcover ISBN:
eBook ISBN:

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About the Serial Editor

Frederick Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

Affiliations and Expertise

Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA