Advances in Heterocyclic Chemistry

Advances in Heterocyclic Chemistry

1st Edition - July 4, 2022

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  • Editors: Eric Scriven, Christopher Ramsden
  • eBook ISBN: 9780323988605
  • Hardcover ISBN: 9780323988599

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Advances in Heterocyclic Chemistry, Volume 138, the latest release in this definitive series on the field of heterocyclic chemistry, combines descriptive synthetic chemistry and mechanistic insights to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Topics in this new release include The Paal Knorr reaction in Heterocyclic Chemistry, Synthesis and Applications of Heterocyclic Sulfoximines, Recent advances in the synthesis of 4H-chromen-4-ones (2012-2021), Recent Developments in the Chemistry of Heteroporphyrins and Heterocarbaporphyrins, The Chemistry of 1,4-Dihydropyrrolo[3,2-b]pyrroles, and more.

Key Features

  • Considered the definitive serial in the field of heterocyclic chemistry
  • Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists
  • Provides the latest comprehensive reviews written by established authorities in the field
  • Combines descriptive synthetic chemistry and mechanistic insights to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds


Graduate students and research workers in academic and industrial laboratories, organic chemists, polymer chemists and biological scientists

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Contributors
  • Preface
  • Chapter One: Paal–Knorr synthesis: An old reaction, new perspectives
  • Abstract
  • 1: Introduction
  • 2: Pyrrole synthesis
  • 3: Furan synthesis
  • 4: Thiophene synthesis
  • 5: Total synthesis of natural products
  • 6: Conclusion
  • Acknowledgment
  • References
  • Chapter Two: Strategies for the synthesis of sulfoximine-containing heterocycles
  • Abstract
  • 1: Introduction
  • 2: Physical properties of sulfoximines
  • 3: Exocyclic sulfoximine heterocycles
  • 4: Endocyclic sulfoximine heterocycles
  • 5: Conclusion
  • References
  • Chapter Three: Recent advances in the synthesis of 4H-chromen-4-ones (2012 − 2021)
  • Abstract
  • 1: Introduction
  • 2: Synthesis of 2,3-unsubstituted 4H-chromen-4-ones
  • 3: Synthesis of 2-substituted 4H-chromen-4-ones
  • 4: Synthesis of 3-substituted 4H-chromen-4-ones
  • 5: Synthesis of 2,3-disubstituted 4H-chromen-4-ones
  • 6: Conclusions
  • Acknowledgments
  • References
  • Chapter Four: Recent developments in the chemistry of heteroporphyrins and heterocarbaporphyrins
  • Abstract
  • 1: Introduction
  • 2: meso-Unsubstituted mono- and diheteroporphyrins and related annulated systems
  • 3: meso-Substituted mono- and diheteroporphyrins and their coordination complexes
  • 4: meso-Substituted heteroporphyrins with fused aromatic rings
  • 5: Telluraporphyrins and porphyrinoids derived therefrom
  • 6: Carbazole-derived heteroporphyrins and related systems
  • 7: Tetraoxa-, tetrathia- and tetraselenaporphyrin dications and related systems
  • 8: Phosphaporphyrins
  • 9: Silaporphyrins
  • 10: Carbaporphyrinoid systems
  • 11: Heterocarbaporphyrins
  • 12: Heteroazuliporphyrins
  • 13: Heterobenziporphyrins
  • 14: Hetero-N-confused porphyrins and X-confused heteroporphyrins
  • 15: Miscellaneous heteroporphyrinoid systems
  • 16: Contracted heteroporphyrins
  • 17: Conclusions
  • Acknowledgments
  • References
  • Chapter Five: The chemistry of 1,4-dihydropyrrolo[3,2-b]pyrroles
  • Abstract
  • 1: Introduction
  • 2: Synthesis
  • 3: Reactivity
  • 4: Photophysical properties
  • 5: Applications
  • 6: Summary and outlook
  • References
  • Index

Product details

  • No. of pages: 434
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: July 4, 2022
  • Imprint: Academic Press
  • eBook ISBN: 9780323988605
  • Hardcover ISBN: 9780323988599

About the Editors

Eric Scriven

Eric Scriven was educated in the UK and appointed lecturer in organic chemistry at the University of Salford in 1971. He joined Reilly Industries in 1979, and was Head of Research & Development 1991-2003. He is now Publishing Editor of Arkivoc and is based at the Department of Chemistry, University of Florida in Gainesville. His research interests are in heterocyclic chemistry, especially pyridines. He has over 100 publications and patents in heterocyclic chemistry. He has also published and consulted in the field of technology management. He was a founding editor (with Hans Suschitzky) of Progress in Heterocyclic Chemistry now in its 25th year. He has collaborated with Alan Katritzky and others as an Editor-in-Chief of Comprehensive Heterocyclic Chemistry 2nd and 3rd editions. He has edited two other works, Azides and Nitrenes (1984), and Pyridines (2013).

Affiliations and Expertise

Publishing Editor of Arkivoc, Department of Chemistry, University of Florida, Gainesville, USA

Christopher Ramsden

Chris Ramsden was born in Manchester, UK in 1946. He is a graduate of Sheffield University and received his PhD in 1970 for a thesis entitled ‘Meso-ionic Compounds’ (W. D. Ollis) and a DSc in 1990. Subsequently he was a Robert A. Welch Postdoctoral Fellow at the University of Texas (with M. J. S. Dewar)(1971-3), working on the development and application of semi-empirical MO methods, and an ICI Postdoctoral Fellow at the University of East Anglia (with A. R. Katritzky)(1973-6), working on the synthesis of novel heterocycles. In 1976 he moved to the pharmaceutical industry and was Head of Medicinal Chemistry (1986-1992) at Rhone-Poulenc, London. He moved to Keele University as Professor of Organic Chemistry in 1992, where he is now Emeritus Professor. His research interests include the structure and preparation of novel heterocycles, three-centre bonding in the context of the chemistry of betaines and hypervalent species, and the properties of the enzyme tyrosinase and related ortho-quinone chemistry. He was an Editor-in-Chief of ‘Comprehensive Heterocyclic Chemistry III’ and a co-author of ‘The Handbook of Heterocyclic Chemistry, 3rd Edn, 2010.

Affiliations and Expertise

Professor of Organic Chemistry, Keele University, Staffordshire, UK

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