Advances in Heterocyclic Chemistry, Volume 123

Chapter One. Developments in Tetrazole Chemistry (2009–16)
V.A. Ostrovskii, E.A. Popova and R.E. Trifonov

• 1. Introduction
• 2. Fundamental Aspects and Theoretical Calculations
• 3. Synthesis and Reactivity of Tetrazoles
• 4. Important Compounds and Applications
• 5. Concluding Remarks

Chapter Two. The Synthesis and Chemistry of Azolobenzodiazepines
K. Hemming

• 1. Introduction
• 2. Imidazobenzodiazepines
• 3. Pyrrolobenzodiazepines
• 4. Pyrazolobenzodiazepines
• 5. Triazolobenzodiazepines
• 6. Oxazolobenzodiazepines
• 7. Tetrazolobenzodiazepines
• 8. Conclusions

Chapter Three. Synthesis and Applications of Thiophene Derivatives as Organic Materials
G. Barbarella, M. Zangoli and F. Di Maria

• 1. Introduction
• 2. Synthesis of Oligo- and Polythiophenes
• 3. Oligo- and Polythiophenes in Organic (Opto)Electronics
• 4. Thiophene Oligomers as Fluorescent Probes in Biological Systems
• 5. Oligo/Polythiophene-Based Nanoparticles and Microfibers
• 6. Concluding Remarks

Chapter Four. Thiophene-Based Quinomethane Analogs
R.A. Aitken and A.D. Harper

• 1. Introduction
• 2. 3-Alkylidenethiophen-2-ones
• 3. 2-Alkylidenethiophen-3-ones
• 4. 5-Alkylidenethiophen-2-ones

Chapter Five. A Synopsis of the Properties and Applications of Heteroaromatic Rings in Medicinal Chemistry
N.A. Meanwell

• 1. Introduction
• 2. A Survey of Properties of 5- and 6-Membered Heteroaromatic Rings of Relevance to Drug Design
• 3. Applications of Heteroaromatic Rings in Drug Design
• 4. Epilogue

Advances in Heterocyclic Chemistry, Volume 123 brings together the fields of biology and organic chemistry, highlighting the ways they increasingly intersect. This updated volume includes a section on new developments in tetrazole chemistry, a section on the synthesis and applications of thiophene derivatives as organic materials, and a synopsis of the properties and applications on heteroaromatic rings in medicinal chemistry. Written by established authorities from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

This definitive series in the field will be of great value to organic chemists, polymer chemists and many biological scientists.

• Considered the definitive serial in the field of heterocyclic chemistry
• Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists
• Provides the latest comprehensive reviews as written by established authorities in the field
• Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic chemistry

Graduate students and research workers in academic and industrial laboratories, organic chemists, polymer chemists and biological scientists