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Advances in Heterocyclic Chemistry - 1st Edition - ISBN: 9780128119730, 9780128119938

Advances in Heterocyclic Chemistry, Volume 122

1st Edition

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Serial Volume Editors: Eric Scriven Christopher Ramsden
Hardcover ISBN: 9780128119730
eBook ISBN: 9780128119938
Imprint: Academic Press
Published Date: 25th March 2017
Page Count: 334
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Table of Contents

Chapter One. Recent Developments in the Chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines

  • 1. Introduction
  • 2. 3-Arylisoxazoles
  • 3. 3-Aryl-2-isoxazolines

Chapter Two. Diketene as Privileged Synthon in the Syntheses of Heterocycles Part 1: Four- and Five-Membered Ring Heterocycles

  • 1. Introduction
  • 2. Syntheses of Four-Membered Heterocycles
  • 3. Synthesis of Five-Membered Heterocycles
  • 4. Conclusion

Chapter Three. Synthesis of Heterocycles From Amidrazones

  • 1. Introduction
  • 2. Synthesis of Five-Membered Rings With Two Heteroatoms
  • 3. Synthesis of Five-Membered Rings With Three Heteroatoms
  • 4. Synthesis of Five-Membered Rings With Four Heteroatoms
  • 5. Synthesis of Fused Five-Membered Rings
  • 6. Synthesis of Six-Membered Rings With One Heteroatom
  • 7. Synthesis of Six-Membered Ring With Two Heteroatoms
  • 8. Synthesis of Six-Membered Rings With Three Heteroatoms
  • 9. Synthesis of Seven-Membered Rings With Three Heteroatoms

Chapter Four. 2-Pyridone Methides (2-Methylene-1,2-dihydropyridines) and Benzo-Fused Analogs—Part 1: Synthesis

  • 1. Introduction
  • 2. Occurrence and Synthesis

Chapter Five. Synthesis of Piperidines and Dehydropiperidines: Construction of the Six-Membered Ring

  • 1. Introduction
  • 2. Intramolecular Pathways via Ring-Closing Reactions
  • 3. Intermolecular Heterocycle Construction

Chapter Six. The Literature of Heterocyclic Chemistry, Part XIV, 2014

  • 1. Introduction
  • 2. General Sources and Topics
  • 3. Three-Membered Rings
  • 4. Four-Membered Rings
  • 5. Five-Membered Rings
  • 6. Six-Membered Rings
  • 7. Rings With More than Six Members
  • 8. Heterocycles Containing Unusual Heteroatoms
  • Appendix A. Supplementary data


Advances in Heterocyclic Chemistry is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. As the most recent release in the series, this book specifically focuses on new developments in the chemistry of 3-Arylisoxazoles and 3-Aryl-2-isoxazolines, and the synthesis of hererocycles from Amidrazones, amongst other important updates. Written by established, global authorities in the field, this comprehensive, continuously updated, longstanding series combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds.

Key Features

  • Serves as the go-to reference for organic chemists, polymer chemists, and many biological scientists
  • Provides the latest comprehensive reviews written by established authorities in the field
  • Combines descriptive synthetic chemistry and mechanistic insight to show how chemistry drives the preparation and useful properties of heterocyclic compounds


Graduate students and research workers in academic and industrial laboratories, organic chemists, polymer chemists and biological scientists


No. of pages:
© Academic Press 2017
25th March 2017
Academic Press
Hardcover ISBN:
eBook ISBN:

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About the Serial Volume Editors

Eric Scriven

Eric Scriven was educated in the UK and appointed lecturer in organic chemistry at the University of Salford in 1971. He joined Reilly Industries in 1979, and was Head of Research & Development 1991-2003. He is now Publishing Editor of Arkivoc and is based at the Department of Chemistry, University of Florida in Gainesville. His research interests are in heterocyclic chemistry, especially pyridines. He has over 100 publications and patents in heterocyclic chemistry. He has also published and consulted in the field of technology management. He was a founding editor (with Hans Suschitzky) of Progress in Heterocyclic Chemistry now in its 25th year. He has collaborated with Alan Katritzky and others as an Editor-in-Chief of Comprehensive Heterocyclic Chemistry 2nd and 3rd editions. He has edited two other works, Azides and Nitrenes (1984), and Pyridines (2013).

Affiliations and Expertise

Department of Chemistry, University of Florida, Gainesville, USA

Christopher Ramsden

Chris Ramsden was born in Manchester, UK in 1946. He is a graduate of Sheffield University and received his PhD in 1970 for a thesis entitled ‘Meso-ionic Compounds’ (W. D. Ollis) and a DSc in 1990. Subsequently he was a Robert A. Welch Postdoctoral Fellow at the University of Texas (with M. J. S. Dewar)(1971-3), working on the development and application of semi-empirical MO methods, and an ICI Postdoctoral Fellow at the University of East Anglia (with A. R. Katritzky)(1973-6), working on the synthesis of novel heterocycles. In 1976 he moved to the pharmaceutical industry and was Head of Medicinal Chemistry (1986-1992) at Rhone-Poulenc, London. He moved to Keele University as Professor of Organic Chemistry in 1992, where he is now Emeritus Professor. His research interests include the structure and preparation of novel heterocycles, three-centre bonding in the context of the chemistry of betaines and hypervalent species, and the properties of the enzyme tyrosinase and related ortho-quinone chemistry. He was an Editor-in-Chief of ‘Comprehensive Heterocyclic Chemistry III’ and a co-author of ‘The Handbook of Heterocyclic Chemistry, 3rd Edn, 2010.

Affiliations and Expertise

Keele University, Staffordshire, UK