Advances in Genetics

Advances in Genetics

1st Edition - February 19, 1997

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  • Editors: Jeffrey Hall, Jay Dunlap, Theodore Friedmann, Francesco Giannelli
  • eBook ISBN: 9780080568225

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Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.This volume of Advances in Genetics continues the series goal to present both human and molecular genetic reviews in a timely fashion. Anderson and Kay investigate CAB gene expression in the regulation of gene transcriptions in plants. Harmon and Allan offer a historical overview of apoptosis and its recent heightened interest. Developments involving four X-linked disorders and their resulting increased susceptibility to infection are presented by Smithand Notarangelo. Dickson and colleagues present research on the role of dystrophin in Duchenne muscular dystrophy and the potential feasibility of gene therapy in curing this disease as well as other diseases involving the heart and central nervous system. The relationship between mice and humans and the ways in which they help each other understand gene function and relationship is presented by Elizabeth Fisher. Timmons and Shearn summarize what information has been learned about prune, Killer of prune, and the prune/Killer of prune lethal interactions: rare genetic phenomena in Drosophila melanogaster. Meiotic recombination, via the breaking and rejoining of DNA and the subsequent reciprocal exchange and the cytological evidence of the exchange, are explored by Ross et al. Last, Coonar and McKenna discuss the four major cardiomyopathies, focusing on recent advances in hypertrophic cardiomyopathy.


Graduate students and researchers in all facets of genetics: molecular, cell, and developmental biology, as well as human genetic medicine.

Table of Contents

  • S.L. Anderson and S.A. Kay, Phototransduction and Circadian Clock Pathways Regulating Gene Transcription in Higher Plants.
    L.O. Ross, C.A. Bascom-Slack, and D.S. Dawson, Chiasmata, Crossovers, and Meiotic Chromosome Segregation.
    B.V. Harmon and D.J. Allan, Apoptosis.
    C.I.E. Smith and L.D. Notarangelo, Molecular Basis for X-Linked Immunodeficiencies.
    A. Fassati, S. Murphy, and G. Dickson, Gene Therapy of Duchenne Muscular Dystrophy.
    A.S. Coonar and W.J. McKenna, Molecular Genetics of Familial Cardiomyopathies.
    E.M.C. Fisher, The Contribution of the Mouse to Advances in Human Genetics.
    L. Timmons and A. Shearn, Prune/Killer of Prune: A Conditional Dominant Lethal Interaction if Drosophila.
    Subject Index.

Product details

  • No. of pages: 331
  • Language: English
  • Copyright: © Academic Press 1997
  • Published: February 19, 1997
  • Imprint: Academic Press
  • eBook ISBN: 9780080568225

About the Serial Volume Editors

Jeffrey Hall

Affiliations and Expertise

Brandeis University, Waltham, MA, USA

Jay Dunlap

Affiliations and Expertise

The Geisel School of Medicine, Dartmouth, NH, USA

Theodore Friedmann

School of Medicine, University of California at San Diego, USA

Affiliations and Expertise

School of Medicine, University of California at San Diego, USA

Francesco Giannelli

Affiliations and Expertise

United Medical and Dental Schools of Guy’s and St. Thomas’ Hospitals, London, U.K.

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