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Advances in Genetics - 1st Edition - ISBN: 9780123864819, 9780123864826

Advances in Genetics, Volume 76

1st Edition

Serial Editor: Stephen F. Goodwin
Hardcover ISBN: 9780123864819
eBook ISBN: 9780123864826
Imprint: Academic Press
Published Date: 2nd December 2011
Page Count: 152
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Table of Contents

Series Page


Sensory Functions for Degenerin/Epithelial Sodium Channels (DEG/ENaC)

I. Introduction

II. Chemosensation

III. Mechanosensation

IV. Peripheral Pain

V. Conclusions

Genetic and Phenotypic Consequences of Introgression Between Humans and Neanderthals

I. Introduction

II. The First Genetic Evidence for Introgression in Our Species

III. Evidence for Introgression Obtained from Present-Day Human Genomes

IV. History of Hominans in Europe

V. Comparison of Middle European Neanderthal Nuclear DNA with Modern Human Nuclear DNA

VI. The ABBA–BABA Test for Introgression

VII. Different Regions of the Neanderthal Genome are Found in Different Modern Humans

VIII. The Genetic Contribution of the Denisovans to Our Species

IX. Possible Range of Phenotypic Impacts of Neanderthal and Denisovan Introgressions into Modern Humans


Genomic Approaches to Understanding Hox Gene Function

I. Introduction: Historical Perspective

II. The Molecular Genetics of Hox Complexes: Conservation and Colinearity

III. Hox Target Genes and Functions

IV. Early Experiments to Identify Hox Target Genes

V. Genomic Approaches to Identifying Hox Target Genes

VI. Microarray Expression Profiling

VII. ChIP Approaches

VIII. Computational Approaches

IX. Prospects

GATA Transcription Factors in the Developing Reproductive System

I. Introduction

II. Molecular Control of Gonadal Development

III. Canonical WNT Signaling Control of Gonadal Development

IV. The GATA–FOG Transcriptional Partnership

V. GATA4–FOG2 Control of Gonadal Development

VI. Conclusions



The field of Genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. Advances in Genetics continually publishes important, timely reviews from leaders in the field that cover a broad range of topics of interest to geneticists and their colleagues in affiliated disciplines.

Key Features

  • Important, timely reviews from leaders in the field
  • Cover a broad range of topics of interest to geneticists and their colleagues in affiliated disciplines


Geneticists, molecular biologists, neurobiologists


No. of pages:
© Academic Press 2011
2nd December 2011
Academic Press
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Editor

Stephen F. Goodwin

Dr. Stephen Goodwin works at the University of Oxford.

Affiliations and Expertise

University of Oxford, UK