Advances in Genetics, Volume 79

Serial Editors

Contributors

Chapter One From Pluripotency to Islets

I Introduction

II miRNAs and Embryonic Stem Cells

III miRNAs and Embryonic Stem Cell Pluripotency

IV miRNAs that Regulate Early Cell Fate Decisions in human ESC

V miRNAs that Regulate Endoderm and Pancreatic Precursor Formation

VI miRNAs that Regulate Pancreatic Endocrine Cell Function

VII Conclusions and Future Directions

Chapter Two The Genetics of Dystonias

I Introduction

II Clinical Features

III Primary Dystonia

IV Dystonia Plus

V Heredodegenerative Dystonia

VI Dystonia in Association with other Neurogenetic Disorders

VII Conclusions

Chapter Three Exome Sequencing and Advances in Crop Improvement

I Introduction

II Sequencing: Tools and Techniques

III Exome Sequencing for Crop Improvement

IV Crop Improvement Beyond Exome Sequencing

V Conclusions

Competing Interests

Abbreviations

Chapter Four Applications of Functional Protein Microarrays in Basic and Clinical Research

I Introduction

II Fabrication of Functional Protein Microarrays

III Signal Detection

IV Applications of Functional Protein Microarrays

V Outlook

Index

The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes imporatnt reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

• Includes methods for testing with ethical, legal, and social implications

Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists, and biochemists.