Description

Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Genetics continues the series goal to present both human and molecular genetic reviews in a timely fashion. Anderson and Kay investigate CAB gene expression in the regulation of gene transcriptions in plants. Harmon and Allan offer a historical overview of apoptosis and its recent heightened interest. Developments involving four X-linked disorders and their resulting increased susceptibility to infection are presented by Smithand Notarangelo. Dickson and colleagues present research on the role of dystrophin in Duchenne muscular dystrophy and the potential feasibility of gene therapy in curing this disease as well as other diseases involving the heart and central nervous system. The relationship between mice and humans and the ways in which they help each other understand gene function and relationship is presented by Elizabeth Fisher. Timmons and Shearn summarize what information has been learned about prune, Killer of prune, and the prune/Killer of prune lethal interactions: rare genetic phenomena in Drosophila melanogaster. Meiotic recombination, via the breaking and rejoining of DNA and the subsequent reciprocal exchange and the cytological evidence of the exchange, are explored by Ross et al. Last, Coonar and McKenna discuss the four major cardiomyopathies, focusing on recent advances in hypertrophic cardiomyopathy.

Readership

Graduate students and researchers in all facets of genetics: molecular, cell, and developmental biology, as well as human genetic medicine.

Table of Contents

S.L. Anderson and S.A. Kay, Phototransduction and Circadian Clock Pathways Regulating Gene Transcription in Higher Plants. L.O. Ross, C.A. Bascom-Slack, and D.S. Dawson, Chiasmata, Crossovers, and Meiotic Chromosome Segregation. B.V. Harmon and D.J. Allan, Apoptosis. C.I.E. Smith and L.D. Notarangelo, Molecular Basis for X-Linked Immunodeficiencies. A. Fassati, S. Murphy, and G. Dickson, Gene Therapy of Duchenne Muscular Dystrophy. A.S. Coonar and W.J. McKenna, Molecular Genetics of Familial Cardiomyopathies. E.M.C. Fisher, The Contribution of the Mouse to Advances in Human Genetics. L. Timmons and A. Shearn, Prune/Killer of Prune: A Conditional Dominant Lethal Interaction if Drosophila. Subject Index.

Details

No. of pages:
331
Language:
English
Copyright:
© 1997
Published:
Imprint:
Academic Press
Print ISBN:
9780120176359
Electronic ISBN:
9780080568225

Reviews

@from:Praise for the Series @qu:"Outstanding both in variety and in the quality of its contributions." @source:--NATURE @qu:"Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics." @source:--SCIENCE @qu:"The high standards of the Advances series of Academic Press are now almost taken for granted. The new volume matches up to the revolutionary and all-embracing developments in genetics that have occurred over the last few years." @source:--SCIENCE PROGRESS @qu:"This text would be of interest to geneticists, botanists, developmental biologists, molecular biologists, and other interested individuals." @source:--BIOLOGICAL ABSTRACTS @qu:"Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines."