Advances in Drug Delivery Systems, 6

1st Edition

Proceedings of the Sixth International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, U.S.A., February 21-24, 1993

Editors: James M. Anderson Sung Wan Kim Jindrich Kopeček
Hardcover ISBN: 9780444820273
eBook ISBN: 9781483161570
Imprint: Elsevier
Published Date: 1st January 1994
Page Count: 372
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Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology.

The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes.

The book examines the factors on in vitro micelle stability of adriamycin-block copolymer conjugates; vaginal and reproductive system treatments using a bioadhesive polymer; and control of the disposition profiles of proteins in the kidney via chemical modification. The publication also takes a look at drug delivery using biodegradable microspheres; approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer; and biodegradable microspheres for the delivery of oral vaccines.

The selection is a valuable source material for scientists and readers interested in the advances in the systems of drug delivery.

Table of Contents

Novel Drug Delivery Systems

Biologically Engineered Microstructures: Controlled Release Applications

New Approaches to Targeting Bioactive Compounds

Mucosal Delivery of Macromolecules

Targeted Delivery of Diagnostic Agents by Surface-Modified Liposomes

Influencing Factors on in Vitro Micelle Stability of Adriamycin-Block Copolymer Conjugates

SK&F 110679: Comparison of Absorption Following Oral or Respiratory Administration

Bioavailability of Pulmonary Delivered Peptides and Proteins: α-Interferon, Calcitonins and Parathyroid Hormones

Vaginal and Reproductive System Treatments Using a Bioadhesive Polymer

Peptide and Protein Delivery

Paracellular Transport of a Proteolytically Labile Pentapeptide Across the Colonic and Other Intestinal Segments of the Albino Rabbit: Implications for Peptide Drug Design

Control of the Disposition Profiles of Proteins in the Kidney Via Chemical Modification

Drug Delivery Using Biodegradable Microspheres

Biodegradable Microspheres for the Delivery of Oral Vaccines

pH/Temperature-Sensitive Polymers for Macromolecular Drug Loading and Release

Targeting and Cellular Recognition in Drug Delivery

Antibodies as Targeting Moieties: Affinity Measurements, Conjugation Chemistry and Applications in Immunoliposomes

Approaches to Improved Antibody- and Peptide-Mediated Targeting for Imaging and Therapy of Cancer

Bacterial Cell Killing by Antibody Targeted Photolysis: Enhanced Effect by OH Radical Generation

Antibody-Directed Enzyme Prodrug Therapy (Adept)

Targeting the Vasculature of Solid Tumors

Synthesis of the Conjugate of Superoxide Dismutase with the Copolymer of Divinyl Ether and Maleic Anhydride Retaining Enzymatic Activity

Bioadhesive N-(2-Hydro


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© Elsevier 1994
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About the Editor

James M. Anderson

Sung Wan Kim

Jindrich Kopeček