Table of Contents
- List of Contributors. Preface (L.H. Hurley, J.B. Chaires).
Part I: Methods used to evaluate the molecular basis for sequence specificity.
Calorimetric studies of drug-DNA interactions (L.A. Marky et al.). Molecular modeling of drug-DNA interactions: facts and fantasies (J.O. Trent, S. Neidle). X-Ray crystallographic and NMR structural studies of anthracycline snticancer drugs: implication in drug design (A.H.-J. Wang). Transcriptional assay for [robing molecular aspects of drug-DNA interactions (D.R. Phillips).
Part II: Sequence Specificity of DNA Interactive Drugs.
Molecular recognition of DNA by daunorubicin (J.B. Chaires). Covalent interactions of ethidium and actinomycin D with nucleic acids: photoaffinity labeling of DNA (D.E. Graves). DNA binding of dinuclear platinum complexes (N. Farrell). DNA sequence selectivity of the pyrrole-derived, bifunctional alkylating agents (P.B. Hopkins). Index.
- No. of pages: 246
- Language: English
- Copyright: © Elsevier Science 1996
- Published: July 9, 1996
- Imprint: Elsevier Science
- Hardcover ISBN: 9781559381666
- eBook ISBN: 9780080526140
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