Advances in Clinical Cytology

Advances in Clinical Cytology

1st Edition - January 1, 1981

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  • Authors: Leopold G. Koss, Dulcie V. Coleman
  • eBook ISBN: 9781483191911

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Advances in Clinical Cytology describes the ultrastructural dynamics of endometrial hyperplasia and neoplasia. This book contains 11 chapters that evaluate the meaning of endometrial aspiration in gynecological application and address the morphologic response of hyperplastic and neoplastic endometrium to exogenous progestogens. Some of the topics covered in the book are the evaluation of the methods of cytological sampling; population screening for cervical cancer; advances in pulmonary cytology; and selection of high-risk cases of cancer development for screening and collection of specimens. Other chapters deal with the evaluation of cytology as a method of screening, as well as the cytological features of human polyomavirus-infected cells. An analysis of the functional connections between epithelial cells is provided. The concluding chapters are devoted to the morphology of the cell surface and the method for staining smears. The book can provide useful information to doctors, cytologists, students, and researchers.

Table of Contents

  • Preface

    1 The Ultrastructural Dynamics of Endometrial Hyperplasia and Neoplasia


    Normal Cyclic Endometrium

    Endometrial Hyperplasia

    Endometrial Neoplasia

    Morphologic Response of Hyperplastic And Neoplastic Endometrium to Exogenous Progestogens


    2 The Value of Endometrial Aspiration in Gynaecological Practice


    Methods of Cytological Sampling

    Interpretation of Endometrial Aspirates

    Evaluation of Aspiration Techniques

    Clinical Application


    3 An Evaluation of Population Screening for Cervical Cancer


    The Screening Test

    Natural History

    Evaluation of Outcome


    Economic Considerations


    4 Recent Advances in Pulmonary Cytology: Early Detection and Localization of Occult Lung Cancer in Symptomless Males


    Selection of High-Risk Cases for Screening and Collection of Specimens

    Cytological Classification of Sputum Samples

    Localization of Radiographically Occult Bronchogenic Carcinoma

    Management of Patients With Positive Sputum Cytology and Negative Chest X-Ray

    Technique for the Examination of Resected Specimens in Cases of Occult Carcinoma

    Illustrative Cases

    Evaluation of Cytology as a Method of Screening


    5 The Cytological Diagnosis of Human Polyomavirus Infection and Its Value in Clinical Practice


    The Human Polyomaviruses BK and JC

    Methods Of Detection

    Cytological Appearance of Human Polyomavirus-Infected Cells

    Contribution of Cytology to the Knowledge of Infection with the Human Polyomaviruses

    Prospects for Research


    6 Cell Relationships in Epithelia


    Morphology of the Cell Surface

    Functional Relationships Between Epithelial Cells

    Pathological Cell Relationships


    7 Aspiration Biopsy Cytology in Diseases of the Thyroid



    Comparison of Fine-Needle Aspiration with Other Methods of Needle Biopsy

    Cytological Diagnosis of Non-Neoplastic Thyroid Disorders

    Thyroid Neoplasms

    Evaluation of the Cytological Method


    8 Cytology of Ophthalmological Diseases


    Collection of Specimens

    Normal Cytology

    Inflammatory Diseases

    Benign Ocular Lesions

    Malignant Ocular Lesions


    9 Smear Preparations in the Diagnosis of Malignant Lesions of the Central Nervous System


    Method for Staining Smears

    Findings in Various Tumor Types

    10 Configurations of Surfaces of Cells in Effusions by Scanning Electron Microscopy


    Technical Methods


    Configuration of Surfaces of Cells in Fluids


    11 Automation In Cytology: Computerized High Resolution Scanning of Cervical Smears


    Strategy of Automation


    Information Derived from Computed Cell Images

    Cell Image Preprocessing

    Cell Image Features

    Cell Classification

    Objective Cytodiagnosis

    The Statistical Sampling Requirements for Prescreening Devices


    Color Plate Section Facing Page


Product details

  • No. of pages: 368
  • Language: English
  • Copyright: © Butterworth-Heinemann 1986
  • Published: January 1, 1981
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483191911

About the Authors

Leopold G. Koss

Dulcie V. Coleman

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