Preface. H. Fujii and S. Miwa, Red Blood Cell Enzymes and Their Clinical Application. A. Beishuizen, I. Vermes, and C. Haanen, Endogenous Mediators in Sepsis and Septic Shock. S. Narayanan and N. Hamasaki, Current Concepts of Coagulation and Fibrinolysis. K.J. Azziz, Tumor Markers: Reclassification and New Approaches to Evaluation. Subject Index.