Description

Volume 63 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

Key Features

  • Expertise of international contributors
  • Latest cutting-edge technologies
  • Comprehensive in scope

Readership

Clinical Laboratory Professionals, Physicians and Research Scientists

Table of Contents

  • Contributors
  • Preface
  • Chapter One. Vitamin D Binding Protein: A Multifunctional Protein of Clinical Importance
    • Abstract
    • 1 Introduction
    • 2 Identification of DBP Polymorphisms and Its Geographical Distribution
    • 3 Analytical Issues
    • 4 The Multifunctional Character of DBP (Fig. 1.3)
    • 5 Clinical Importance of DBP in Cancer (Table 1.1A)
    • 6 Clinical Importance of DBP in Noncancer-Related Diseases (Table 1.1B)
    • 7 DBP as a Therapeutic Agent
    • References
  • Chapter Two. Free Testosterone: Clinical Utility and Important Analytical Aspects of Measurement
    • Abstract
    • Abbreviations
    • 1 Androgen Physiology
    • 2 Clinical Utility of Measuring Testosterone
    • 3 Laboratory Methods for Measuring Free and BAT
    • 4 Conclusions
    • References
  • Chapter Three. Urine Retinol-Binding Protein 4: A Functional Biomarker of the Proximal Renal Tubule
    • Abstract
    • 1 Introduction
    • 2 Nomenclature
    • 3 History
    • 4 Molecular Structure, Interactions, and Transport of Plasma RBP4
    • 5 Renal Handling of RBP4 and Other Plasma Proteins
    • 6 RBP4 in Plasma and Urine Excretion
    • 7 uRBP4 Assay
    • 8 Stability of uRBP4
    • 9 Clinical Application of uRBP4 Measurement
    • 10 Toxicology and Drug Effects
    • 11 HIV Disease
    • 12 Summary
    • 13 Executive Summary
    • References
  • Chapter Four. Proteomics for Breast Cancer Urine Biomarkers
    • Abstract
    • Abbreviations
    • 1 Introduction
    • 2 Current BC Biomarker Studies Using Proteomics
    • 3 Urine as a Potential Source for Biomarkers
    • 4 Potential Urine Biomarkers Identified Using Proteomic Techniques in BC
    • 5 Key Proteomic Techniques in Urine Biomarker Research
    • 6 Conclusion

Details

No. of pages:
332
Language:
English
Copyright:
© 2014
Published:
Imprint:
Academic Press
eBook ISBN:
9780128003565
Print ISBN:
9780128000946