Description

Volume 55 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.

Key Features

  • Leading experts from academia and clinical laboratory science
  • Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies

Readership

Biochemists and clinical biochemists

Table of Contents

  • Contributors
  • Preface
  • HE4 in ovarian cancer
    • 1. Abstract
    • 2. Introduction
    • 3. CA125
    • 4. Biomarker Identification: From Genomics to Proteomics
    • 5. Clinical Validation of a Tumor Biomarker
    • 6. HE4: Discovery to Clinical Application
    • 7. Conclusions
  • Salivary Transcriptome Biomarkers in Oral Squamous Cell Cancer Detection
    • 1. Abstract
    • 2. Introduction
    • 3. The Salivary Transcriptome: Characterization and Biomarker Discovery
    • 4. Etiopathology of OSCC: The Field Cancerization Theory
    • 5. Molecular Alterations in OSCC
    • 6. Biomarkers: Adequate Study Design (PRoBE Design)
    • 7. Outlook, Conclusion, and the Oral Fluid Nanosensor Test
  • Laminin isoform profiles in salivary glands in Sjögren's syndrome
    • Abbreviations
    • 1. Abstract
    • 2. Sjögren's Syndrome
    • 3. Structure of the Human Labial Salivary Glands
    • 4. Basement Membrane
    • 5. Laminins
    • 6. LM Receptors
    • 7. Regulation of LMs in Salivary Glands
    • 8. Conclusion
    • Acknowledgments
  • Adipokine actions on cartilage homeostasis
    • Abbreviations
    • 1. Abstract
    • 2. Introduction
    • 3. Relevance of Adipokines in Cartilage Disease
    • 4. Measurement of Adipokines
    • 5. Adipokines and Cartilage Homeostasis: Integrated View and Perspectives
  • Chemical Biology of Homocysteine Thiolactone and Related Metabolites
    • Abbreviations
    • 1. Abstract
    • 2. Introduction
    • 3. Homocysteine Thiolactone
    • 4. N-Homocysteinylated Proteins
    • 5. Nε-Homocysteinyl-lysine
    • 6. Conclusions
  • Iron overload in nonalcoholic steatohepatitis
    • Abbreviations
    • 1. Abstract
    • <

Details

No. of pages:
176
Language:
English
Copyright:
© 2011
Published:
Imprint:
Academic Press
eBook ISBN:
9780123870438
Print ISBN:
9780123870421