The heme catabolic pathway and its protective effects on oxidative stress-mediated diseases. Cyclooxygenase-2 and Tumor Biology. Oligonucleotide probes for RNA-targeted fluorescence in situ hybridization. Activin A in brain injury. Methods for Predicting Human Drug Metabolism. A Summary Analysis of Down Syndrome Markers in the Late First Trimester. Estrogen Hydroxylation in Osteoporosis. Cytochrome p450 – another player in the myocardial infarction game?
Volume 43 of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. In this volume, the biochemistry of bilirubin, the end-product of heme metabolism, is explored with respect to its potential beneficial role in preventing oxidative changes associated with a variety of pathological conditions, including atherosclerosis, cancer, and inflammatory, autoimmune and other degenerative diseases.
Biochemists and clinical biochemists.
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- © Academic Press 2007
- 27th December 2006
- Academic Press
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Dr Gregory S Makowski is a board certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in his joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President and Chief Scientific Officer for Clinical Laboratory Partners in Newington CT, USA.
Clinical Laboratory Partners, Newington; Hartford Hospital, Hartford; Department of Laboratory Medicine, University of Connecticut Health Center, Farmington, CT, USA