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Advances in Clinical Chemistry
1st Edition, Volume 73 - March 3, 2016
Editor: Gregory S. Makowski
Language: English
Hardback ISBN:9780128046906
9 7 8 - 0 - 1 2 - 8 0 4 6 9 0 - 6
eBook ISBN:9780128048412
9 7 8 - 0 - 1 2 - 8 0 4 8 4 1 - 2
Advances in Clinical Chemistry, Volume 73, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laborator…Read more
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Advances in Clinical Chemistry, Volume 73, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.
Contains the expertise of international contributors
Provides the latest cutting-edge technologies in the field
Authored by world-renowned clinical laboratory scientists, physicians, and research scientists
Clinical Laboratory Professionals, Physicians and Research Scientists
Chapter One: Antibodies to Phosphatidylserine/Prothrombin Complex in Antiphospholipid Syndrome: Analytical and Clinical Perspectives
Abstract
1 Introduction
2 Historic Background to aPL
3 “Criteria” Antiphospholipid Antibody Tests
4 aPL and Pathogenesis of APS
5 Antibodies to Phosphatidylserine/Prothrombin Complex
6 Clinical and Laboratory Significance of aPS/PT Antibodies
7 Analytic and Diagnostic Challenges Associated with aPS/PT Antibodies
8 Perspectives and Opportunities for the Future
9 Conclusion
Chapter Two: Copeptin in Heart Failure
Abstract
1 Introduction
2 Neurohormonal Activation in HF
3 The Vasopressin System in HF
4 Limitations of Vasopressin Measurements in Clinical Settings
5 Structure and Function of Copeptin
6 Copeptin in Healthy Populations
7 Copeptin in Other Heart Diseases than HF
8 Copeptin in HF
9 Association of Copeptin and Hyponatremia in HF
10 Copeptin and Comorbidity in HF
11 Copeptin and Medical Therapy in HF
12 Conclusion and Future Perspectives on Copeptin in HF
Acknowledgments
Chapter Three: Immunosensors in Clinical Laboratory Diagnostics
Abstract
1 Introduction
2 Classification of Immunosensors
3 Applications of Immunosensors for Clinical Diagnostics
4 Final Remarks and Perspectives
Acknowledgments
Chapter Four: Cancer Stem Cell Biomarker Discovery Using Antibody Array Technology
Abstract
1 Introduction
2 Evidence of Cancer Stem Cell Populations in Circulating Tumors: Biomarker-Based CSC Discovery
3 Antibody Array-Based Discovery of Local Cancer Stem Cell Signaling Mechanisms
4 Conclusions
Acknowledgments
Chapter Five: Biochemistry of Statins
Abstract
1 Introduction
2 Structure
3 Pharmacokinetics
4 Mechanism of Action
5 Administration
6 Efficacy
7 Side Effects
8 Statin Intolerance
9 Conclusion
Chapter Six: The Importance of Magnesium in the Human Body: A Systematic Literature Review
Abstract
1 Introduction
2 Method
3 Results
4 Discussion
5 Conclusion
Chapter Seven: Inborn Errors of Metabolism
Abstract
1 Inborn Errors of Metabolism
No. of pages: 268
Language: English
Edition: 1
Volume: 73
Published: March 3, 2016
Imprint: Academic Press
Hardback ISBN: 9780128046906
eBook ISBN: 9780128048412
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in his joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President and Chief Scientific Officer for Clinical Laboratory Partners in Newington CT, USA.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USA
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