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Advances in Carbohydrate Chemistry and Biochemistry
1st Edition, Volume 73 - October 28, 2016
Editor: David C. Baker
Language: English
Hardback ISBN:9780128099834
9 7 8 - 0 - 1 2 - 8 0 9 9 8 3 - 4
eBook ISBN:9780128099841
9 7 8 - 0 - 1 2 - 8 0 9 9 8 4 - 1
Advances in Carbohydrate Chemistry and Biochemistry has provided, since its inception in 1945, critical and informative articles written by research specialists that integrate…Read more
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Advances in Carbohydrate Chemistry and Biochemistry has provided, since its inception in 1945, critical and informative articles written by research specialists that integrate the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology to the study of carbohydrates. Its articles present a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.
Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry, and research
Integrates the industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates
Informs and updates on all the latest developments in the field
Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology
Chapter One: Stevia Glycosides: Chemical and Enzymatic Modifications of Their Carbohydrate Moieties to Improve the Sweet-Tasting Quality
Abstract
1 Introduction
2 Steviol Glycoside Structures from S. rebaudiana
3 Steviol Variants of Glycoside Structures from S. rebaudiana
4 Stability of Steviol Glycosides
5 Structure–Sweetness Relationship
6 Chemical Modifications of Steviol Glycosides
7 Enzymatic Modifications of Steviol Glycosides
8 Patents Regarding Enzymatic Modifications of Steviol Glycosides
9 Concluding Remarks
Addendum
Acknowledgments
Chapter Two: Endoglycosidases for the Synthesis of Polysaccharides and Glycoconjugates
Abstract
1 Introduction
2 Endoglycosidases in the Synthesis of Natural and Artificial Polysaccharides
3 Endoglycosidases in the Synthesis of N-Glycopeptides and N-Glycoproteins
4 Endoglycosidases for the Synthesis of Neoglycolipids and Glycosphingolipids
5 Concluding Remarks
Acknowledgment
Chapter Three: Recent Advances Toward Robust N-Protecting Groups for Glucosamine as Required for Glycosylation Strategies
Abstract
1 Introduction
2 The Glycosylation Reaction
3 Acyclic N-Protecting Groups
4 Cyclic N-Protecting Groups
5 Latent Amino-Protecting Groups
6 Conclusions
Acknowledgments
Chapter Four: Carbohydrate-Processing Enzymes of the Lysosome: Diseases Caused by Misfolded Mutants and Sugar Mimetics as Correcting Pharmacological Chaperones
Abstract
1 Introduction
2 Carbohydrate-Processing Enzymes of the Glycosphingolipid Degradation Pathway
3 Lysosomal Glycogen Degradation and Glycogen Storage Disease
4 Enzymes of the Glycoprotein Degradation Pathway and Glycoproteinoses
5 Enzymes Involved in Mucopolysaccharide Degradation and Mucopolysaccharidoses
6 Conclusions and Outlook
No. of pages: 356
Language: English
Edition: 1
Volume: 73
Published: October 28, 2016
Imprint: Academic Press
Hardback ISBN: 9780128099834
eBook ISBN: 9780128099841
DB
David C. Baker
Prof. David C. Baker has a broad research and teaching experience in the organic and medicinal chemistry of the carbohydrates, including nucleosides and cell-surface carbohydrates that are documented in over 200 publications, presentations, and patents. He was elected a Fellow of the American Chemical Society where he has been active principally in the Division of Carbohydrate Chemistry.
Affiliations and expertise
Professor of Chemistry, University of Tennessee in Knoxville, TN, USA
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