Advances in Carbohydrate Chemistry and Biochemistry - 1st Edition - ISBN: 9780123965271, 9780123965073

Advances in Carbohydrate Chemistry and Biochemistry, Volume 67

1st Edition

Serial Volume Editors: Derek Horton
Hardcover ISBN: 9780123965271
eBook ISBN: 9780123965073
Imprint: Academic Press
Published Date: 27th July 2012
Page Count: 290
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Table of Contents

  • Contributors to Volume 383
  • Preface
  • Nathan Sharon
    • The Early Years
    • Love Affair with Soybean Agglutinin and Other Lectins
    • Biological Effects of Plant Lectins
    • Lectins as Tools for the Study of Membranes and Separations of Cells
    • Lectins Involved in Host—Microbial Recognitions
    • Animal Lectins in Cell Recognition
    • Teacher, Educator, Collector, Swimmer, and Curious Traveler
  • Chapter 2 Combining Computational Chemistry and Crystallography for a Better Understanding of the Structure of Cellulose
    • I Introduction
    • II Information from Crystals of Related Small Molecules
    • III Energy Calculations
    • IV Detection of New Stabilizing Interactions in Cellulose with Atoms-in-Molecules Theory
    • V Modeling Crystals of Cellulose
    • VI Conclusions
    • Appendix Molecular Structure Drawings for Saccharide Analogues Having β-(1   →   4) Linkages
  • Chapter 3 Strategies in Synthesis of Heparin/Heparan Sulfate Oligosaccharides
    • I Introduction
    • II Linear Synthesis
    • III Active–Latent Glycosylation Strategy
    • IV Selective Activation
    • V Reactivity-Based Chemoselective Glycosylation
    • VI Reactivity-Independent, Pre-Activation-Based, Chemoselective Glycosylation
    • VII Chemoenzymatic Synthesis
    • VIII Future Outlook
  • Chapter 4 Chemical Synthesis of Glycosylphosphatidylinositol Anchors
    • I Introduction
    • II Classic Approaches to GPI Synthesis
    • III Diversity-Oriented Approaches to GPI Synthesis
    • IV Conclusions and Outlook
  • Chapter 5 Effect of Protein Dynamics and Solvent in Ligand Recognition by Promiscuous Aminoglycoside-Modifying Enzymes
    • I Introduction
    • II Aminoglycoside Antibiotics
    • III Aminoglycoside-Modifying Enzymes
    • IV Thermodynamic Properties of Enzyme–AG Complexes
    • V Protein Dynamics in Substrate Recognition and Substrate Promiscuity of AGMEs
    • VI Conclusions and Future Considerations
  • Author Index
  • Subject Index

Description

  • Contributors to Volume 383
  • Preface
  • Nathan Sharon
    • The Early Years
    • Love Affair with Soybean Agglutinin and Other Lectins
    • Biological Effects of Plant Lectins
    • Lectins as Tools for the Study of Membranes and Separations of Cells
    • Lectins Involved in Host—Microbial Recognitions
    • Animal Lectins in Cell Recognition
    • Teacher, Educator, Collector, Swimmer, and Curious Traveler
  • Chapter 2 Combining Computational Chemistry and Crystallography for a Better Understanding of the Structure of Cellulose
    • I Introduction
    • II Information from Crystals of Related Small Molecules
    • III Energy Calculations
    • IV Detection of New Stabilizing Interactions in Cellulose with Atoms-in-Molecules Theory
    • V Modeling Crystals of Cellulose
    • VI Conclusions
    • Appendix Molecular Structure Drawings for Saccharide Analogues Having β-(1   →   4) Linkages
  • Chapter 3 Strategies in Synthesis of Heparin/Heparan Sulfate Oligosaccharides
    • I Introduction
    • II Linear Synthesis
    • III Active–Latent Glycosylation Strategy
    • IV Selective Activation
    • V Reactivity-Based Chemoselective Glycosylation
    • VI Reactivity-Independent, Pre-Activation-Based, Chemoselective Glycosylation
    • VII Chemoenzymatic Synthesis
    • VIII Future Outlook
  • Chapter 4 Chemical Synthesis of Glycosylphosphatidylinositol Anchors
    • I Introduction
    • II Classic Approaches to GPI Synthesis
    • III Diversity-Oriented Approaches to GPI Synthesis
    • IV Conclusions and Outlook
  • Chapter 5 Effect of Protein Dynamics and Solvent in Ligand Recognition by Promiscuous Aminoglycoside-Modifying Enzymes
    • I Introduction
    • II Aminoglycoside Antibiotics
    • III Aminoglycoside-Modifying Enzymes
    • IV Thermodynamic Properties of Enzyme–AG Complexes
    • V Protein Dynamics in Substrate Recognition and Substrate Promiscuity of AGMEs
    • VI Conclusions and Future Considerations
  • Author Index
  • Subject Index

Key Features

  • Contributions from leading authorities
  • Informs and updates on all the latest developments in the field

Readership

Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology


Details

No. of pages:
290
Language:
English
Copyright:
© Academic Press 2012
Published:
Imprint:
Academic Press
eBook ISBN:
9780123965073
Hardcover ISBN:
9780123965271

Reviews

"A series that has established an enviable reputation for a consistently high quality of content and production, and that is of outstanding value." --Journal of American Chemical Society


About the Serial Volume Editors

Derek Horton Serial Volume Editor

Affiliations and Expertise

The American University, Washington, DC, USA