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Advances in Carbohydrate Chemistry and Biochemistry - 1st Edition - ISBN: 9780128001288, 9780128008058

Advances in Carbohydrate Chemistry and Biochemistry, Volume 71

1st Edition

Serial Volume Editor: Derek Horton
eBook ISBN: 9780128008058
Hardcover ISBN: 9780128001288
Imprint: Academic Press
Published Date: 2nd December 2014
Page Count: 506
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Table of Contents

  • Preface
  • Serge David
  • Chapter 1: Carbohydrate–Protein Interactions: Molecular Modeling Insights
    • Abstract
    • I Introduction
    • II Specific Features of Carbohydrate Modeling
    • III Experimental Data on Protein–Carbohydrate Interactions
    • IV Features of Protein–Carbohydrate Interactions
    • V Computational Tools for Docking Carbohydrates on Proteins
    • VI Carbohydrate Biosynthesis and GTs
    • VII Recognition
    • VIII Glycoside Hydrolases
    • IX Conclusion and Perspectives
    • Acknowledgments
  • Chapter 2: Chemical Synthesis of Saponins
    • Abstract
    • I Introduction
    • II General Considerations on Saponin Synthesis
    • III Synthesis of Plant Saponins
    • IV Synthesis of Marine Saponins
    • V Summary and Outlook
    • Acknowledgments
  • Chapter 3: Nitrogen-Containing Macrocycles Having a Carbohydrate Scaffold
    • Abstract
    • I Introduction
    • II Aza-Crown Ethers Containing a Carbohydrate Subunit
    • III Cyclic Homooligomers from Amino Sugars
    • IV Sugar-Based Cryptands
    • V Cyclic Peptides Containing Amino Sugar Units
    • VI Nitrogen-Containing Glycophanes
    • VII 1,2,3-Triazole-Containing Synthetic Cyclodextrin Analogues
    • VIII Summary and Outlook
    • Acknowledgments
  • Chapter 4: Mechanism-Based Inhibitors of Glycosidases: Design and Applications
    • Abstract
    • I Introduction
    • II Activity-Based Probes
    • III Toward Activity-Based Probes for Retaining β-Glucosidases
    • IV Perspectives for Activity-Based Probes Targeting Retaining β-Glucosidases
    • V Concluding Remarks
  • Chapter 5: Modulating LPS Signal Transduction at the LPS Receptor Complex with Synthetic Lipid A Analogues
    • Abstract
    • I Introduction
    • II Immune Response to LPSs
    • III The LPS Receptor Complex
    • IV Host-Derived Mediators and the Pathogenesis of Sepsis
    • V Modulation of the LPS Receptor Complex by Lipid A Analogues
    • VI Summary and Conclusions
    • Acknowledgments
  • Author Index
  • Subject Index


Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

Key Features

  • Features contributions from leading authorities and industry experts
  • Informs and updates on all the latest developments in the field


Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology.


No. of pages:
© Academic Press 2014
2nd December 2014
Academic Press
eBook ISBN:
Hardcover ISBN:


"A series that has established an enviable reputation for a consistently high quality of content and production, and that is of outstanding value." --Journal of American Chemical Society

Ratings and Reviews

About the Serial Volume Editor

Derek Horton

Derek Horton

Affiliations and Expertise

The American University, Washington, DC, USA