Description

Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

Key Features

  • Features contributions from leading authorities and industry experts
  • Informs and updates on all the latest developments in the field
  • Readership

    Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology.

    Table of Contents

    Obituaries 1. Stephen John Charles Angyal

    The Andrews Lectures

    Administration

    Acknowledgments

    List of Publications by S. J. Angyal

    Obituaries 2. John Grant Buchanan

    List of Publications by J. Grant Buchanan

    Obituaries 3. Saul Roseman

    Biosynthesis and Metabolism of Simple Sugars

    Biosynthesis of Mucin Glycoproteins and Brain Gangliosides

    Discovery of the Sialyltransferase Catalyzing the In Vitro Biosynthesis of Sialyl-Lactose

    Biosynthesis of Oligoglycosyl-Glycoproteins Studied at the Johns Hopkins University (1965–1970)

    Bacterial Phosphotransferase System (PTS) Studied at the Johns Hopkins University (1965–1985)

    Intercellular Adhesion and the “Fish Theory” from the Johns Hopkins University (1966–1972)

    Degradation of Chitin and Hexosamine Metabolism in the Sea World (1985–2011)

    Acknowledgments

    References

    Chapter 4. De novo asymmetric synthesis of the pyranoses: From monosaccharides to oligosaccharides

    Abstract

    Abbreviations

    I Introduction

    II Masamune–Sharpless Approach to the Hexoses

    III Danishefsky Hetereo-Diels–Alder Approach to Various Pyranoses

    IV MacMillan Iterative Aldol Approach to Various Pyranoses

    V Asymmetric Oxidative Biocatalytic Aldol Approach to Various Pyranoses

    VI Sharpless Dihydroxylation/Enzymatic Aldol Approach 2-Ketoses

    VII Non-De Novo Asymmetric Approaches to Pyranoses

    VIII O’Doherty De Novo Approach to Pyranoses

    Acknowledgments

    References

    Chapter 5. Recent advances toward the development of inhibitors to attenuate tumor metastasis via the interruption of lectin–ligand interactions

    Abstract

    Abbreviations

    I Introduction

    II Roles of Carbohydrates in Tumor Development

    III Roles of Lectins in Tumor Development

    IV Developing Antican

    Details

    No. of pages:
    320
    Language:
    English
    Copyright:
    © 2013
    Published:
    Imprint:
    Academic Press
    Print ISBN:
    9780124080935
    Electronic ISBN:
    9780124081130

    Reviews

    "A series that has established an enviable reputation for a consistently high quality of content and production, and that is of outstanding value." --Journal of American Chemical Society