Description

Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

Key Features

  • Features contributions from leading authorities and industry experts
  • Informs and updates on all the latest developments in the field

Readership

Researchers in biochemistry, organic chemistry, medicinal chemistry and instrumentation methodology

Table of Contents

Obituaries 1. Stephen John Charles Angyal

The Andrews Lectures

Administration

Acknowledgments

List of Publications by S. J. Angyal

Obituaries 2. John Grant Buchanan

List of Publications by J. Grant Buchanan

Obituaries 3. Saul Roseman

Biosynthesis and Metabolism of Simple Sugars

Biosynthesis of Mucin Glycoproteins and Brain Gangliosides

Discovery of the Sialyltransferase Catalyzing the In Vitro Biosynthesis of Sialyl-Lactose

Biosynthesis of Oligoglycosyl-Glycoproteins Studied at the Johns Hopkins University (1965–1970)

Bacterial Phosphotransferase System (PTS) Studied at the Johns Hopkins University (1965–1985)

Intercellular Adhesion and the “Fish Theory” from the Johns Hopkins University (1966–1972)

Degradation of Chitin and Hexosamine Metabolism in the Sea World (1985–2011)

Acknowledgments

References

Chapter 4. De novo asymmetric synthesis of the pyranoses: From monosaccharides to oligosaccharides

Abstract

Abbreviations

I Introduction

II Masamune–Sharpless Approach to the Hexoses

III Danishefsky Hetereo-Diels–Alder Approach to Various Pyranoses

IV MacMillan Iterative Aldol Approach to Various Pyranoses

V Asymmetric Oxidative Biocatalytic Aldol Approach to Various Pyranoses

VI Sharpless Dihydroxylation/Enzymatic Aldol Approach 2-Ketoses

VII Non-De Novo Asymmetric Approaches to Pyranoses

VIII O’Doherty De Novo Approach to Pyranoses

Acknowledgments

References

Chapter 5. Recent advances toward the development of inhibitors to attenuate tumor metastasis via the interruption of lectin–ligand interactions

Abstract

Abbreviations

I Introduction

II Roles of Carbohydrates in Tumor Development

III Roles of Lectins in Tumor Development

IV Developing Antican

Details

No. of pages:
320
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Electronic ISBN:
9780124081130
Print ISBN:
9780124080935

About the serial-volume-editor

Reviews

"A series that has established an enviable reputation for a consistently high quality of content and production, and that is of outstanding value." --Journal of American Chemical Society