Beginning as chemical curiosities, carbenes are now solidly established as reactive intermediates with fascinating and productive research areas of their own. Five decades of divalent carbon chemistry have provided us with a vast repertoire of new, unusual and surprising reactions. Some of those reactions, once classified as exotic, have become standard methods in organic synthesis. These highly reactive carbene species have been harnessed and put to work to achieve difficult synthetic tasks that other reactive intermediates cannot easily perform. The fruitful relationship between experiment and theory has pushed carbene chemistry further toward the direction of reaction control; that is, regio- and stereoselectivity in intra- and intermolecular addition and insertion reactions. The interplay between experiment and modern spectroscopy has led to the characterisation of many carbenes that are crucial to both an understanding and a further development of this field. Understanding of carbene chemistry has advanced dramatically, especially in the last decade, and new developments continue to emerge. Some of the recent exciting findings have been collected in the first volume of Advances in Carbene Chemistry. With this second volume, the series will continue to provide a periodic coverage of carbene chemistry in its broadest sense - leading into the next century.
For organic chemists with an interest in Carbene chemistry.
Table of Contents
Preface (U.H. Brinker). 1,2-Hydrogen migration in carbenes: laser-flash photolysis and beyond (R. Bonneau, M.T.H. Lui). Chemistry of carbenes in molecular reaction vessels (U.H. Brinker, M.G. Rosenberg). Thermochemistry of carbenes (P. Chen). The carbene route to bridgehead double bonds (M. Jones, Jnr). High resolution fluorescence spectroscopy: determination of the zero-field splitting parameters of excited triplet states of aromatic carbenes (E. Migirdicyan, B. Kozankiewicz). Issues and challenges in the chemistry of alkylcarbenes (M.S. Platz). Persistent triplet carbenes (H. Tomioka). Laser flash photolysis studies of carbonyl carbenes (J.P. Toscano). Diamino-, Amino(oxy)-, Dioxy-, Amino(thio)-, Oxy(thio)-, and dithiocarbenes (J. Warkentin).