Description

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.

Key Features

  • Provides information on cancer research
  • Oustanding and original reviews
  • Suitable for researchers and students

Readership

Researchers and students in the basic and clinical sciences of cancer biology and oncology, plus related areas in genetics, immunology, pharmacology, cell biology, and molecular biology.

Table of Contents

Contributors

Chapter One. Bioengineering Strategies for Designing Targeted Cancer Therapies

1 Introduction

2 Cancer-Targeting Mechanisms

3 Design Criteria for Cancer Targeting

4 Delivery Vehicles

5 Targeting Moieties

6 Drug Release

7 Future Directions in Cancer Targeting

8 Concluding Remarks

Acknowledgments

References

Chapter Two. Autophagy: Cancer’s Friend or Foe?

1 Introduction

2 Autophagy and Autophagic Death

3 Autophagy in Tumor Initiation and Development

4 Autophagy in Tumor Progression and Metastasis

5 Autophagy in Tumor Dormancy

6 Autophagy in Cancer Initiating/Stem Cells

7 Autophagy in Cancer Therapy

8 Conclusions

Acknowledgments

References

Chapter Three. The Transcription Factor FOXM1 (Forkhead box M1): Proliferation-Specific Expression, Transcription Factor Function, Target Genes, Mouse Models, and Normal Biological Roles

1 FOXM1 is an Activating Transcription Factor

2 The Four Known FOXM1 Splice Variants

3 FOXM1 Target Genes

4 Molecular Mechanisms of FOXM1 for Gene Regulation

5 The Molecular Function of FOXM1 as a Conventional Transcription Factor

6 The FOXM1 Expression

7 FOXM1 Mouse Models

8 Biological Functions of FOXM1

References

Index

Details

No. of pages:
416
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Print ISBN:
9780124071735
Electronic ISBN:
9780124072039

Reviews

Praise for the Serial
"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences." --American Scientist
"Excellent, highly informative, in-depth reviews…expertly written, up-to-date, and well-referenced." --Journal of Medicinal Chemistry
"This is a series that has a long tradition of excellence in the field of cancer biology." --Doody’s Publishing Reviews