Advances in Biological and Medical Physics

Volume 4

1st Edition - January 1, 1956
Editors: John H. Lawrence, Cornelius A. Tobias
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 2 - 8 1 7 7 - 3

Advances in Biological and Medical Physics, Volume IV, provides an overview of the state of knowledge in biological and medical physics. The book contains eight chapters and opens… Read more

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Advances in Biological and Medical Physics, Volume IV, provides an overview of the state of knowledge in biological and medical physics. The book contains eight chapters and opens with a discussion of the application of X-ray diffraction to crystalline proteins. This is followed by separate chapters on the relationship between the chemical information which can be stored in the nucleic acid molecule and the sequence of amino acids found in polypeptides and proteins; materials for the biophysical and biochemical study of cell division; and the action of high and low temperatures in the destruction of unicellular organisms. Subsequent chapters deal with infrared spectrometry; the kinetics of iron metabolism; the gross composition of the body; and an argument for a theory of aging, which states that the tendency toward further disease experience is at a metabolic rate determined by accumulated disease experience of the past.

Contributors to Volume IV

Foreword

X-ray Diffraction Applied to Crystalline Proteins

I. Introduction

II. Crystals

III. X-ray Diffraction by a Crystal

IV. Symmetry of Crystal Lattices

V. Determination of Molecular Weights

VI. The Solvent Content of Protein Crystals

VII. The Densities of Protein Crystals

VIII. The Intensities of the Bragg Reflections

IX. The Patterson Function

X. Patterson Functions of Proteins

XI. The Electron Density of a Crystal

XII. Results

XIII. Theories of Protein Structure

References

The Problem of Information Transfer from the Nucleic Acids to Proteins

I. Introduction

II. The Relation of the Nucleic Acids to Protein Synthesis

III. Empirical Evidence

IV. Nucleic Acid-Protein Coding Schemes

V. Various Statistical Considerations

VI. Conclusions

References

Materials for the Biophysical and Biochemical Study of Cell Division

I. The Problem of Cell Division—Introduction

II. Patterns of Cell Division

III. Problems of the Stimulation of Mitosis

IV. The Preparation for Mitosis

V. Biochemistry and Biophysics of Mitosis

VI. Cytokinesis: Division of the Cell Body

VII. The Interpretation of Experiments with Antimitotic Agents

References

Lethal Effects of High and Low Temperatures on Unicellular Organisms

I. Introduction

II. Heat Inactivation

III. Cold Inactivation

IV. Conclusions and Desirable Extensions of Existing Work

References

Infrared Spectrometry

I. Introduction

II. Interpretation of Infrared Spectra

III. Instrumentation

IV. Infrared Microspectrometry

V. Experimental Techniques

VI. Applications in Biological Chemistry

VII. Conclusion

References

Kinetics of Iron Metabolism

The Gross Composition of the Body

I. Introduction

II. Body Water

III. Measurement of Total Body Water

IV. Measurement of Extracellular Fluid

V. Fat

VI. Measurement of Fat

VII. Protein and Mineral

References

A Special Consideration of the Aging Process, Disease, and Life Expectancy

I. Life Span and Age-Specific Death Rate

II. Internal Homogeneity of Populations with Regard to Subpopulations, Physiologic Age, and Tendency Toward Disease

III. Major Disease Groups

IV. The Onset of Disease and Life Expectancy

V. Summary

References

Author Index

Subject Index