Advances in Biological and Medical Physics

Contributors to Volume IForewordHeavy and Radioactive Isotopes in Clinical and Experimental Medicine I. Introduction II. The Medical Significance of Isotopes III. Clinical Applications of Isotopes IV. Some Applications of Isotopes in Experimental Medicine ReferencesNitrogen and Carbon Isotopes: Their Application in Vivo to the Study of the Animal Organism I. Introduction II. Methods III. The Metabolism of Nitrogen Compounds IV. Carbohydrate and Fat Metabolism V. Conclusion ReferencesThe Nature and Production of Artificial Radioactivity I. The Nature of Radioactivity II. Nuclear Relactions III. Chemical Factors in Radioisotope Production IV. Availability of Radioisotopes General References Specific ReferencesFundamentals of Radioactivity and Its Instrumentation I. Interaction of Radiation with Matter II. Radioactivity Units and Standards III. Basic Instruments for the Detection of Ionizing Radiations ReferencesHealth-Physics, Instrumentation, and Radiation Protection I. Scope of Health-Physics II. Past Experience in Protection III. Exposure Standards IV. Organization and Functions of a Typical Health-Physics Group V. Instruments VI. Some Elementary Formula and Calculation Methods ReferencesThe Use of Radioactive Isotopes in the Study of Iron and Hemoglobin Metabolism and the Physiology of the Erythrocyte I. Introduction II. Absorption of Iron III. Distribution and Transport of Iron IV. Excretion of Iron V. Miscellaneous Experimental Procedures Using Tagged Iron VI. Effect of Various Conditions on Iron Uptake VII, Iron Metabolism in Pathologic States VIII. Red Cells Tagged with Radio Iron ReferencesRadioactive Phosphorus: Its Application to the Study of Phospholipid Metabolism I. Introduction IL Some General Considerations on the Use of Radioactive Phosphorus as a Labeling Agent in the Animal Body III. The Amounts of Administered Incorporated into Phospholipids by Tissues of the Animal Body IV. How P32 Qan Be Used to Measure the Rate of Turnover of Phospholipid in the Animal Body V. Problems in Phospholipid Metabolism to Which P^^ Has Been Successfully Applied VI. Summary ReferencesIodine Metabolism I. Introduction II. The Entry and Distribution of Iodine in the Body III. The Fate of Iodine in the Thyroid Gland IV. The Mechanism of the Excretion of Iodized Compounds From the Thyroid V. The Fate of the Iodized Compounds Excreted by the Thyroid VI. Influence of Various Factors on Iodine Metabolism VII. Conclusion ReferencesThe Effects of the Atomic Bomb Irradiation on the Japanese I. Introduction II. Nature of the Physical Agents III. Types of Injury (General) IV. ClinicalandPathologicalEffectsof Whole Body Irradiation in Animals V. Clinical Manifestations VI. Pathological Findings VII. SummaryNucleic Acid Metabolism I. Introduction II. Structure of the Nucleic Acids III. Nucleic Acid Ck)ntent of Tissues IV. Nuclear and Cytoplasmic Nucleic Acids V. Biological Synthesis of Purine Compounds VI. Application of Isotopic Indicators in the Study of the Turnover of Nucleic Acids VII. P32 Content of Residual Phosphorus VIII. Incorporation of P32 into Desoxyribosenucleic Acid IX. Incorporation of P32 into Ribosenucleic Acid X. Desoxyribosenucleic Acid Turnover and Cell Division XI. Application of Labeled Desoxyribosenucleic Acid in the Determination of the Life-Cycle of the Red Corpuscles of the Hen XII. Intravenous Transfer of P32 from Chromatin to Hepatic Tissue XIII. Studies of Virus Reproduction with P32 as a Tracer XIV. Enzymatic Studies with Labeled Desoxyribosenucleic Acid as a Substrate XV. Effect of Roentgen Rays on the Formation of Labeled Desoxyribosenucleic Acid XVI. Effect of Beta Rays Endtted by l^dioactive Colloids Taken Up by the Liver on the Formation of Labeled Desoxyribosenucleic Acid ReferencesAuthor IndexSubject Index