Advances in Behavioral Pharmacology - 1st Edition - ISBN: 9780120047031, 9781483214917

Advances in Behavioral Pharmacology, Volume 3

1st Edition

Editors: Travis Thompson Peter B. Dews William A. McKim
eBook ISBN: 9781483214917
Imprint: Academic Press
Published Date: 28th August 1981
Page Count: 234
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Table of Contents

List of Contributors


Preface to the Ottawa Conference on the Rate-Dependent Effects of Drugs

Contents of Previous Volumes

Rate-Dependence and the Effects of Benzodiazepines

I. Introduction

II. Effects of Benzodiazepines on Overall Rates of Responding Maintained by Different Schedules of Reinforcement

III. Effects of Benzodiazepines on Local Response Rates on Fixed-Interval Schedules

IV. Effects of Benzodiazepines on Punished Responding

V. Conclusions


Rate-Dependence and the Effects of Phenothiazine Antipsychotics in Pigeons

I. Introduction

II. Effects of Phenothiazines on Multiple Fixed-Ratio, Fixed-Interval Performances

III. Effects of Phenothiazines on Shock-Avoidance Responding

IV. Effects of Phenothiazines on the Stimulus Control of Responding

V. Conclusions


Rate-Convergent Effects of Drugs

I. Introduction: Rate-Dependency

II. Questions about Rate-Dependency

III. Problem: The Definition of Drug Effect

IV. Distributions of Rate-Dependency Slopes

V. Convergence of Rates

VI. Conclusions


Rate-Dependency: A Nonspecific Behavioral Effect of Drugs

I. Introduction

II. Rate-Dependent Effects of Extra Stimuli

III. Rate-Dependent Effects of Drugs and Drug-State Change

IV. Duration of Rate-Dependent Changes Produced by Drugs and Stimuli

V. Effects of Varying the Intensity of ES and Dosage of Drug

VI. Type of Behavior Affected by Drugs and ES

VII. Conclusion


Quantitation in Behavioral Pharmacology

I. Introduction

II. Historical Considerations

III. Mathematical Considerations

IV. Alternative Considerations

V. Conclusions


Rate-Dependency: Scope and Limitations in the Explanation and Analysis of the Behavioral Effects of Drugs

I. Introduction

II. Response Rate and Other Influences on the Behavioral Effects of Drugs

III. Usefulness of Rate Analyses in Understanding the Actions of Drugs

IV. What Gets Changed When a Drug Alters Response Rates?

V. Conceptual Status of the Rate-Dependency Principle

VI. Conclusions


History and Present Status of Rate-Dependency Investigations



Drug Effects on Behaviors Maintained by Different Events

I. Introduction

II. Early Studies

III. Characteristics of Behaviors Maintained by Different Events

IV. Comparisons of Drug Effects on Responding Maintained by Different Events

V. Summary and Conclusions


Oral Self-Administration and the Relevance of Conditioned Taste Aversions

I. Introduction

II. Factors Maintaining Oral Self-Administration

III. Oral Self-Administration of Opioids

IV. Conditioned Taste Aversions Produced by Naloxone

V. Conditioned Taste Aversions Produced by Self-Administered Drugs

VI. Factors Influencing Amphetamine-Produced Taste Aversions

VII. Influence of Conditioned Taste Aversions on Operant Behavior

VIII. A Pharmacological Approach to Conditioned Taste Aversion

IX. Conditioned Anorexia Hypothesis of Taste Aversion

X. Duration of Drug Action and Conditioned Taste Aversion

XI. Summary and Conclusions




Advances in Behavioral Pharmacology, Volume 3 covers papers dealing with various aspects of the ways in which drug effects are related to and perhaps modified by the rate of responding. The book discusses the behavioral actions of benzodiazepines and considers the extent to which these actions are consistent with the proposition that these effects are partially or entirely determined by control rates of responding. The text then describes rate-dependence and the effects of phenothiazine antipsychotics in pigeons; the rate-convergent effects of drugs; and the rate-dependent effects of extra stimuli, of drugs, and drug-state change. Historical, mathematical and alternative considerations in quantitation in behavioral pharmacology, as well as the history and status of rate-dependency investigations are also considered.
The book then tackles the scope and limitations in the explanation and analysis of the behavioral effects of drugs; drug effects on behaviors maintained by different events; and the importance of identifying which of these factors contributes to the behavior studied in any given experiment. Pharmacologists, psychologists, psychiatrists, and students taking these disciplines will find the book useful.


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© Academic Press 1981
Academic Press
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Ratings and Reviews

About the Editors

Travis Thompson Editor

Peter B. Dews Editor

William A. McKim Editor