Advances in Asymmetric Synthesis

Advances in Asymmetric Synthesis

1st Edition - February 18, 1999

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  • Editor: A. Hassner
  • eBook ISBN: 9780080551999

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Enantioselective synthetic methods are not only in the forefront of chemical and pharmaceutical research but activity in this area is constantly increasing. It is stimulated by the urgency to obtain drugs or compounds of medicinal interest as single anantiomers, and the keeness to synthesize natural products in nonracemic form. This volume presents seven chapters from pioneers and authorities in this rapidly expanding field.


For scientists and researchers in the field of asymmetric synthesis.

Table of Contents

  • Preface (A. Hassner).

    Asymmetric synthesis of &Bgr;-amino acids and &Bgr;-lactum derivatives via cunjugate addition of metal amides (Y. Yamamoto et al.).

    Enantioselective deprotonation of cyclic ketones
    (M. Majewski).

    Stereoselective addition of chiral &agr;-aminoorganometallics to aldehydes (R.E. Gawley).

    Asymmetric access to functional, structurally diverse molecules exploiting five-membered heterocyclic silyloxy dienes (G. Casiraghi et al.).

    Asymmetric catalysis using heterobimetallic compounds
    (M. Shibasaki, H. Sasai).

    Palladium-catalyzed enantioselective allylic substitution reactions (S.J. Sesay, J.M.J. Williams).

    New achievements in asymmetric synthesis of organophosphorous compounds (O.I. Kolodiazhnyi).

Product details

  • No. of pages: 364
  • Language: English
  • Copyright: © JAI Press 1999
  • Published: February 18, 1999
  • Imprint: JAI Press
  • eBook ISBN: 9780080551999

About the Editor

A. Hassner

Professor Emeritus, Department of Chemistry, Bar-ilan University, Israel. Alfred Hassner has over 60 years of experience in organic chemistry and has published over 320 scientific articles. He is a leading expert in organic synthesis. He authored the first three editions of “Organic Synthesis Based on Name Reactions” and was editor of three book series (on heterocycles, asymmetric synthesis, cycloadditions). He first introduced the now universally used term “regioselectivity”.

Affiliations and Expertise

Professor Emeritus, Department of Chemistry, Bar-Ilan University, Israel

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