Description

Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.

Readership

Researchers, academics and postgraduates working in medical virology and infectious diseases, chemotherapy and drug discovery

Table of Contents

Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses) Methylenecyclopropane analogues of nucleosides as anti-herpes agents Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates CCR5 antagonists for the treatment of HIV infection and AIDS The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Details

No. of pages:
264
Language:
English
Copyright:
© 2007
Published:
Imprint:
Elsevier Science
eBook ISBN:
9780080548241
Print ISBN:
9780444521736
Print ISBN:
9780444561039

About the editor

E. De Clercq

Affiliations and Expertise

Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium