Description

Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.

Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.

With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject.

Key Features

  • Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds
  • Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing
  • Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Readership

Researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject.

Table of Contents

Contributor contact details

Introduction

Part I: Introduction to chronic wounds

Chapter 1: Dysfunctional wound healing in chronic wounds

Abstract:

1.1 Normal skin wound healing

1.2 Ageing skin and the onset of chronic, dysfunctional wound healing

1.3 Dysfunctional healing of chronic skin wounds

1.4 Conclusions

1.5 Acknowledgements

Chapter 2: The role of micro-organisms and biofilms in dysfunctional wound healing

Abstract:

2.1 Introduction

2.2 Microbiology and biofilms: not mutually exclusive

2.3 Biofilms and the interactive cooperative community

2.4 Biofilms in chronic wounds

2.5 Biofilms as therapeutic or restorative microbiology/modeling

2.6 Conclusion

Chapter 3: Scarring and scarless wound healing

Abstract:

3.1 Introduction

3.2 Wound healing process

3.3 Fibroproliferative scarring

3.4 Scarless fetal wound healing

3.5 Adult versus fetal wound healing

3.6 Treatment options for scars

3.7 Future trends

3.8 Conclusions

Chapter 4: The discovery and development of new therapeutic treatments for the improvement of scarring

Abstract:

4.1 Introduction

4.2 Scar-free and scar-forming healing

4.3 In vitro and in vivo models to investigate the mechanisms of scarring and evaluate potential treatments

4.4 Translation from pre-clinical studies to clinical efficacy

4.5 Understanding the mechanisms of action of prophylactic scar improvement therapies

4.6 Conclusions

Chapter 5: Monitoring chronic wounds and determining treatment

Abstract:

5.1 Introduction

5.2 Wound size measurements

5.3 Wound colour measurements

5.4 Background material

Part II: Biomaterial therapies for chronic wounds

Chapter 6: Functional requirements of wound repair bioma

Details

No. of pages:
672
Language:
English
Copyright:
© 2011
Published:
Imprint:
Woodhead Publishing
Electronic ISBN:
9780857093301
Print ISBN:
9781845697006
Print ISBN:
9780081016992

About the editor

David Farrar

David Farrar is Science Manager for Biomaterials at the Smith and Nephew Research Centre, York, UK

Reviews

"... comprises a nice overview of various kinds of therapies and a sufficiently extensive discussion of important (future) materials and treatments. This without neglecting the basics…"--Biomat.net, April 2013

The book comprises a nice overview of various kinds of therapies and a sufficiently extensive discussion of important (future) materials and treatments., Birgit Stubbe, Biomaterials Network