Advanced Biosensors for Health Care Applications - 1st Edition - ISBN: 9780128157435

Advanced Biosensors for Health Care Applications

1st Edition

Editors: Dr. Inamuddin Raju Khan Ali Mohammad Abdullah M. Asiri
Paperback ISBN: 9780128157435
Imprint: Elsevier
Published Date: 1st May 2019
Page Count: 260
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Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. Biosensors are shown to be superior tools due to their proven high sensitivity and selectivity. Therefore, Advanced Biosensors for healthcare: Materials and Applications highlights different types of prognostic and diagnostic biomarkers associated with cancer diabetes, Alzheimer disease, brain and retinal diseases, cardiovascular diseases, and bacterial infections and various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of above specific diseases. These recent developments on the nanoscale biomedical diagnosis devices described in this book allow these technologies to reach to the market in the near future. The book attempts to describe the need of novel strategies for developing new class of assay systems to retrieve the desired health information of patient in real-time. To achieve accomplishments, the selection of each sensor components and operational parameters of desired property is very crucial to develop an efficient sensing platform. This book explores the potential of nano-multidisciplinary science to design and develop smart sensing technology using micro-nano electrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy i.e., FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-chip (LOC), for diagnostics and personalized health care monitoring.

Key Features

  • Describes advanced nanomaterials for biosensor applications
  • Relates the properties of available nanomaterials to specific biomarkers applications
  • Includes diagnosis and electrochemical studies based on biosensors
  • Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies
  • Describes novel strategies for developing a new class of assay systems to retrieve the desired health information


Biotechnology, biochemical engineering, Chemistry, materials science, biomedical engineering scientists /resaerchers in academia and industry

Table of Contents

1. Advanced nanoparticles: biosensor applications
2. New micro- and nanotechnologies for electrochemical biosensor development
3. Advanced nanostructured materials in biomedical applications
4. Integrated electronics, analytical transducers and signal processing for sensor development
5. Nanobiosensing platforms for in-vitro applications
Aptamer biosensor
Enzymatic biosensor
Disease diagnostics
6. Nanobiosensing platforms forin-vivo applications
Disease detection
Targeted therapeutics
Diagnostic biomarkers
7. Functionalized advanced hybrid materials for biosensing applications
8. Challenges and future prospects of nano-advanced sensing technology
9. Advance functionalized nanoparticles for biomedical applications
10. Electrochemical immunosensor for rapid detection of breast cancer biomarkers
11. Detection of cardiovascular risk biomarkers
12. Advanced nanostructured carbon dot based biomedical applications
13. Advanced conducting polymer nanomaterials for biomedical applications
14. Nanostructured conductive hydrogels-based biosensor platform
15. Advanced nanostructured semiconductor materials biomedical engineering
16. Carbon nanotubes in biomedical applications
17. Application of conducting polymers to genosensors


No. of pages:
© Elsevier 2019
Paperback ISBN:

About the Editor

Dr. Inamuddin

Dr. Inamuddin is an Assistant Professor in the Department of Applied Chemistry, Aligarh Muslim University (AMU), India. He obtained his Masters of Science degree in Organic Chemistry from Chaudhary Charan Singh (CCS) University, Meerut, India, in 2002. He received his Masters and Doctor of Philosophy degrees in Applied Chemistry from AMU in 2004 and 2007, respectively. He has extensive research experience in Analytical Chemistry, Materials Chemistry, Electrochemistry and, more specifically, Renewable Energy and the Environment. He has published 72 research articles in international journals, and eight book chapters. He has also published five edited books with Springer, Nova Science Publishers, CRC Press and Trans Tech Publications. He is an active member of various editorial boards of international journals.

Affiliations and Expertise

Department of Applied Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Raju Khan

Raju Khan is a Senior Scientist & Group Leader at Analytical Chemistry Group, CSIR-North East Institute of Science & Technology, Jorhat, Assam, Govt. of India. He received his MSc degree in Inorganic Chemistry and PhD in Physical Chemistry from Jamia Millia Islamia, Central University, New Delhi, India, 2002 & 2005, respectively. Thereafter, he worked as a Postdoctoral Fellow at the “Sensor Research laboratory” Department of Chemistry, University of the Western Cape, Cape Town, South Africa, in the year 2005-06 and also worked as a Fast Track Young Scientist at CSIR-National Physical Laboratory, New Delhi Govt. of India. Dr Khan was involved in synthesize of novel materials to fabricate electrochemical biosensor to detect target disease risk biomarker for health care monitoring. Dr Khan is also engaged other external project funding National & International collaborative project, Indo-Czech Republic & Indo-Russia. After successful completion of awarded tenure, Dr. Khan joined as Scientist at Analytical Chemistry Division, CSIR-North East Institute of Science and Technology (NEIST), a research laboratory of Council of Scientific and Industrial Research (CSIR), Govt. of India and he is also promoted and currently working as a Senior Scientist. He was awarded the BOYSCAST fellowship to work work as a visiting scientist for one year at University of the Texas at Sanantonio, USA. Since then, Dr. Khan has served with more than 10 years R&D and teaching experience, producing high quality research, mentoring students, and supporting analytical division as outsource facility.

Affiliations and Expertise

CSIR-North East Institute of Science and Technology, Jorhat, Assam, India

Ali Mohammad

Ali Mohammad is Emeritus Professor of Chemistry in the Department of Applied Chemistry, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh, India. His scientific interests include physico-analytical aspects of solid-state reactions, micellar thin layer chromatography, surfactants analysis, and green chromatography. He is the author or coauthor of 250 scientific publications including research articles, reviews, and book chapters. He has also served as editor of Journal, Chemical and Environmental Research being published from India since 1992 and as the Associate Editor for Analytical Chemistry section of the Journal of Indian Chemical Society. He has been the member of editorial boards of Acta Chromatographica, Acta Universitatis Cibiniensis Seria F. Chemia, Air Pollution, and Annals of Agrarian Science. He has attended as well as chaired sessions in various international and nation conferences. Dr. Mohammad obtained his M.Phil. (1975), Ph.D. (1978), and D.Sc. (1996) degrees from Aligarh Muslim University, Aligarh, India. He has supervised 53 students for Ph.D./M.Phil. and M.Tech. degrees.

Affiliations and Expertise

Department of Applied Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

Abdullah M. Asiri

Prof. Abdullah M. Asiri has been the Head of the Chemistry Department at King Abdulaziz University, Saudi Arabia, since October 2009, and he is the founder and the Director of the Center of Excellence for Advanced Materials Research. He graduated from King Abdulaziz University (KAU) with a BSc in Chemistry in 1990 and a PhD from University of Wales, College of Cardiff, UK in 1995. He was promoted to a Professor in 2004. His research interest covers color chemistry, synthesis of novel photochromic, thermochromic systems, synthesis of novel coloring matters and dyeing of textiles, Materials Chemistry, Nanochemistry and nanotechnology Polymers and plastics. He is the main author of ten books in different chemistry disciplines. Prof. Asiri is the Editor-in-Chief of King Abdulaziz University Journal of Science. A major achievement of Prof. Asiri is the discovery of tribochromic compounds, a class of compounds which change from slightly or colorless to deep colored when subjected to small pressure or when grind. This discovery was introduced to the scientific community as a new terminology Published by IUPAC in 2000. This discovery was awarded a patent from European Patent office and from UK patent and some other patents office in Europe. Prof. Asiri has been involved in many committees at the KAU level and also on the national level, he took a major roll in the Advanced materials committee working for KACST to identify the National plan for science and technology in 2007. Prof. Asiri played a major role in advancing the chemistry education and research in KAU, he has been awarded the best Researchers from KAU for the past five years. He also awarded the Young Scientist award from the Saudi Chemical society in 2009, and also the first prize for the distinction in science from the Saudi chemical society in 2012. He also received a recognition certificate from the American Chemical society (Gulf region Chapter) for the advancement of chemical science in the Kingdome. Also he received a Scopus certificate for the most Publishing Scientist in Saudi Arabia in chemistry in 2008.He is also a member of the Editorial Board of Pigments and Resin Technology (UK), Organic Chemistry in Sight (New Zealand), Designed Monomers & Polymers and Journal of Single Molecule Research . He is the Vice- President of Saudi Chemical Society (Western Province Branch).

Affiliations and Expertise

Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia

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