Advanced Biosensors for Health Care Applications highlights the different types of prognostic and diagnostic biomarkers associated with cancer, diabetes, Alzheimer's disease, brain and retinal diseases, cardiovascular diseases, bacterial infections, as well as various types of electrochemical biosensor techniques used for early detection of the potential biomarkers of these diseases. Many advanced nanomaterials have attracted intense interests with their unique optical and electrical properties, high stability, and good biocompatibility. Based on these properties, advanced nanoparticles have been used as biomolecular carriers, signal producers, and signal amplifiers in biosensor design. Recent studies reported that there are several diagnostic methods available, but the major issue is the sensitivity and selectivity of these approaches. This book outlines the need of novel strategies for developing new systems to retrieve health information of patients in real time. It explores the potential of nano-multidisciplinary science in the design and development of smart sensing technology using micro-nanoelectrodes, novel sensing materials, integration with MEMS, miniaturized transduction systems, novel sensing strategy, that is, FET, CMOS, System-on-a-Chip (SoC), Diagnostic-on-a-Chip (DoC), and Lab-on-a-Chip (LOC), for diagnostics and personalized health-care monitoring. It is a useful handbook for specialists in biotechnology and biochemical engineering.
Describes advanced nanomaterials for biosensor applications
Relates the properties of available nanomaterials to specific biomarkers applications
Includes diagnosis and electrochemical studies based on biosensors
Explores the potential of nano-multidisciplinary science to design and develop smart sensing technologies
Describes novel strategies for developing a new class of assay systems to retrieve the desired health information
Biotechnology, biochemical engineering, Chemistry, materials science, biomedical engineering scientists /researchers in academia and industry
Table of Contents
1. Advanced nanoparticle-based biosensors for diagnosing foodborne pathogens 2. Aptamer technology for the detection of food-borne pathogens and toxins 3. Biosensors for rapid detection of breast cancer biomarkers 4. Electrochemical biosensors for antioxidants 5. Electrochemical immunosensors for rapid detection of breast cancer biomarkers 6. Functionalized advanced hybrid materials for biosensing applications 7. Smart, portable and non-invasive diagnostic biosensors for health care 8. Aptamer mediated nanobiosensing for health monitoring 9. Biosensing-drug delivery systems for in vivo applications 10. Nanobodies and their in vivo applications 11. New micro- and nanotechnologies for electrochemical biosensor development 12. Cholesterol based enzymatic and non-enzymatic sensors 13. Recent trends in sensors for health and agricultural applications 14. Graphene-based functional hybrid materials: Synthesis strategies and its applications in development of chemical and biological sensors 15. Challenges and future prospects of nano-advanced sensing technology
Inamuddin is currently working as an Assistant Professor in the Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia. He is also a permanent faculty member (Assistant Professor) at the Department of Applied Chemistry, Aligarh Muslim University, Aligarh, India. He obtained a Master of Science degree in Organic Chemistry from Chaudhary Charan Singh (CCS) University, Meerut, India, in 2002. He then received his Master of Philosophy and Doctor of Philosophy degrees in Applied Chemistry from Aligarh Muslim University (AMU), India, in 2004 and 2007, respectively. He has extensive research experience in multidisciplinary fields of Analytical Chemistry, Materials Chemistry, and Electrochemistry and, more specifically, renewable energy and environment. He has worked on different research projects as project fellow and senior research fellow funded by University Grants Commission (UGC), Government of India, and Council of Scientific and Industrial Research (CSIR), Government of India. He has received the Fast Track Young Scientist Award from the Department of Science and Technology, India, to work in the area of bending actuators and artificial muscles. He has completed four major research projects sanctioned by University Grant Commission, Department of Science and Technology, Council of Scientific and Industrial Research, and Council of Science and Technology, India. He has published 138 research articles in international journals of repute and eighteen book chapters in knowledge-based book editions published by renowned international publishers. Additionally, he has published forty-two edited books and is an editorial board member and associate editor for a number of journals. He has attended as well as chaired sessions in various international and national conferences. He has worked as a Postdoctoral Fellow, leading a research team at the Creative Research Initiative Center for Bio-Artificial Muscle, Hanyang University, South Korea, in the field of renewable energy, especially biofuel cells. He has also worked as a Postdoctoral Fellow at the Center of Research Excellence in Renewable Energy, King Fahd University of Petroleum and Minerals, Saudi Arabia, in the field of polymer electrolyte membrane fuel cells and computational fluid dynamics of polymer electrolyte membrane fuel cells. His research interest includes ion exchange materials, a sensor for heavy metal ions, biofuel cells, supercapacitors and bending actuators.
Affiliations and Expertise
Assistant Professor, Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia
Dr. Khan is currently working as Principal Scientist at Microfluidics & MEMS Centre, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal - 462026, MP, India. His current research on Bio-molecular separation, including sample preparation and detection, Microchip based separation under the concept of lab-on-a-chip and electrochemical biosensor integrated with microfluidics clinical applications. He has more than 15 years of R&D experience in CSIR & other academics R&D Institutes such as in Analytical Chemistry Group, CSIR-NEIST, Jorhat, Assam, CSIR-NPL, New Delhi and CSIR-AMPRI, Bhopal Govt. of India, respectively. He received his MSc degree in Inorganic Chemistry and Ph.D. in Physical Chemistry from Jamia Millia Islamia, Central University, New Delhi, India, in 2002 & 2005, respectively. After that, he worked as a Postdoctoral Fellow at the “Sensor Research laboratory” Department of Chemistry, University of the Western Cape, Cape Town, South Africa, in the year 2005-06 and also worked as a Fast-Track Young Scientist at CSIR-National Physical Laboratory, New Delhi Govt. of India. Dr. Khan is involved in synthesizing novel materials to fabricate electrochemical biosensors to detect target disease risk biomarker for health care monitoring. Dr. Khan is also engaged in other external project funding by the National & International collaborative project, Indo-Czech Republic & Indo-Russia. He is awarded the reputed BOYSCAST fellowship under the BOYSCAST fellowship scheme from DST and worked as a visiting scientist for one year at the University of Texas at San Antonio, UTSA, USA. Since then, he has published more than 80 articles in SCI journals which attracted more than 2700 citations, published nine book chapters in the reputed book of Elsevier and Taylor Francis, and he has also edited five books of Elsevier and Taylor Francis.
Affiliations and Expertise
Principal Scientist and Associate Professor, CSIR-Advanced Materials and Processes Research Institute (AMPRI), MP, India
Ali Mohammad is Emeritus Professor of Chemistry in the Department of Applied Chemistry, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh, India. His scientific interests include physico-analytical aspects of solid-state reactions, micellar thin layer chromatography, surfactants analysis, and green chromatography. He is the author or coauthor of 250 scientific publications including research articles, reviews, and book chapters. He has also served as editor of Journal, Chemical and Environmental Research being published from India since 1992 and as the Associate Editor for Analytical Chemistry section of the Journal of Indian Chemical Society. He has been the member of editorial boards of Acta Chromatographica, Acta Universitatis Cibiniensis Seria F. Chemia, Air Pollution, and Annals of Agrarian Science. He has attended as well as chaired sessions in various international and nation conferences. Dr. Mohammad obtained his M.Phil. (1975), Ph.D. (1978), and D.Sc. (1996) degrees from Aligarh Muslim University, Aligarh, India. He has supervised 53 students for Ph.D./M.Phil. and M.Tech. degrees.
Affiliations and Expertise
Department of Applied Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
Prof. Abdullah M. Asiri is the Head of the Chemistry Department at King Abdulaziz University since October 2009 and he is the founder and the Director of the Center of Excellence for Advanced Materials Research (CEAMR) since 2010 till date. He is the Professor of Organic Photochemistry. His research interest covers color chemistry, synthesis of novel photochromic and thermochromic systems, synthesis of novel coloring matters and dyeing of textiles, materials chemistry, nanochemistry and nanotechnology, polymers and plastics. A major achievement of Prof. Asiri is the discovery of tribochromic compounds, a class of compounds which change from slightly or colorless to deep colored when subjected to small pressure or when grind. This discovery was introduced to the scientific community as a new terminology published by IUPAC in 2000. This discovery was awarded a patent from European Patent office and from UK patent. He is also a member of the Editorial Board of various journals of international repute. He is the Vice- President of Saudi Chemical Society (Western Province Branch). He holds four USA patents, more than 800 Publications in international journals, seven book chapters, and ten books
Affiliations and Expertise
Chemistry Department, Center of Excellence for Advanced Materials Research, King Abdulaziz University,
Jeddah, Saudi Arabia