An Approach to the Molecular Mechanism of Action

1st Edition - January 1, 1973

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  • Authors: M. J. Michelson, E. V. Zeimal
  • eBook ISBN: 9781483145457

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Acetylcholine: An Approach to the Molecular Mechanism of Action is an in-depth study of neurotransmitter system, with much focus on acetylcholine and its action and the cholinergic synapse. The book, divided into seven chapters, covers the following topics: the function of the cholinergic synapse; the movement of ions across membranes; the excitatory postsynaptic potential; the nature of cholinoreceptors and cholinesterases; the structure of its active centers; and the pattern of arrangement of the receptors of the cholinoreceptive membrane. The book also covers the quantitative evaluation of the action of neurotransmitters; the reactive capacity of the acetylcholine molecule and its effects on nerve endings and nerve fibers; and the release of mediators and hormones. The text is recommended for those who specialize in the fields of biology, medicine, biochemistry, and pharmacology, especially those wish to study about the neurotransmitter system, cholinoreceptors, the cholinergic synapse, the acetylcholine, and its action.

Table of Contents

  • Preface


    1. The Function of the Cholinergic Synapse

    2. The Nature of Cholinoreceptors and Cholinesterases and Methods of Study of Their Chemical Structure

    3. The Quantitative Evaluation of the Action of Substances That Stimulate and Block the Cholinoreceptor

    4. The Reactive Capacity of the Acetylcholine Molecule and the Structure of the Active Centers of the Cholinoreceptors and Cholinesterases

    5. Patterns of Arrangement of Individual Receptors on the Cholinoreceptive Membrane

    6. Changes in the Pattern of Arrangement of Cholinoreceptors in the Process of Evolution

    7. Non-synaptic Cholinoreceptors


    Author Index

    Subject Index

Product details

  • No. of pages: 272
  • Language: English
  • Copyright: © Pergamon 1973
  • Published: January 1, 1973
  • Imprint: Pergamon
  • eBook ISBN: 9781483145457

About the Authors

M. J. Michelson

E. V. Zeimal

About the Editors

P. Alexander

Z. M. Bacq

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