Advances in Planar Lipid Bilayers and Liposomes - 1st Edition - ISBN: 9780124115163, 9780124115415

Advances in Planar Lipid Bilayers and Liposomes, Volume 17

1st Edition

A Tribute to Marin D. Mitov

Serial Editors: Ales Iglic
Serial Volume Editors: Julia Genova
eBook ISBN: 9780124115415
Hardcover ISBN: 9780124115163
Imprint: Academic Press
Published Date: 1st June 2013
Page Count: 382
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Table of Contents

Editorial Board



Chapter One. Marin Mitov Lectures: Measuring the Bending Elasticity of Lipid Bilayers

1 Introduction

2 Calculating the Curvatures

3 Volume, Area, and Free Elastic Energy of a Quasi-spherical Vesicle

4 Experimental Quantities

5 Closer to the Reality

6 Formation of Giant Lipid Vesicles

7 Experimental Setup: Stroboscopic Illumination Module

8 Data Processing

9 Conclusion



Chapter Two. Formation of Curved Membranes and Membrane Fusion Processes Studied by Synchrotron X-ray-Scattering Techniques

1 Introduction

2 Synchrotron Light for Membrane Response Analysis

3 Bending and Packing in Curved Membrane Systems

4 Membrane Fusion

5 The Lamellar to Primitive Cubic Phase Transition

6 The Lamellar to Gyroid Cubic Phase Transition

7 The Lamellar to Inverse Hexagonal Phase Transition

8 Conclusion and Perspectives



Chapter Three. Overview of a Quest for Bending Elasticity Measurement

1 Introduction

2 From GUV Fluctuations to Bending Elasticity Measurements

3 Conclusion


Chapter Four. Extracting Interaction Parameters and Intrinsic Properties of Membrane from Correlations of Giant Vesicle Shape Fluctuations

1 Introduction

2 From the Shape Deformations of Lipid Bilayers to the Flickering Technique

3 Material and Methods

4 Extracting Material Parameters from Membrane Conformational Correlation Functions

5 Outlook



Chapter Five. Lipid Bilayers and Membranes: Material Properties

1 Introduction

2 Material Constants of Bilayers and Membranes: Overview and Discussion of Experimental Data

3 Concluding Remarks



Chapter Six. Interaction of Polylysines with the Surface of Lipid Membranes: The Electrostatic and Structural Aspects

1 Introduction

2 Materials and Methods

3 Electrokinetic Measurements in the Liposome Suspension

4 BP of Membranes

5 PL Adsorption at the Lipid Monolayers

6 Isothermal Titration Calorimetry of Liposomes in the Presence of PL

7 AFM of PLs at the Surface of Bilayer

8 Interaction of Lysine with Lipid Membranes

9 Lysine at the Membrane Surface: Analysis by MD

10 Speculations on PL Interaction with Lipid Bilayers



Chapter Seven. Developing Cell-Scale Biomimetic Systems: A Tool for Understanding Membrane Organization and Its Implication in Membrane-Associated Pathological Processes

1 Concept of Membrane Rafts and Their Cellular Functions

2 Cell-Scale Biomimetic Systems as a Tool to Study Membrane Organization and Functioning

3 Effect of Sphingolipids on the Formation of Membrane Domains and Their Morphology in Biomimetic Systems

4 Visualization of Enzyme Activity in Biomimetic Systems

5 Conclusions and Biological Implications



Chapter Eight. Carotenoid–Lipid Interactions

1 Introduction

2 Characteristics of Carotenoids

3 Model Membranes

4 Methods of Investigation

5 Carotenoid–Lipid Interactions


Chapter Nine. Theory of Phase Transitions: From Magnets to Biomembranes

1 Introduction

2 Phase Transitions and Statistical Mechanics

3 Theory of Phase Transitions

4 Effects of the Interaction Potential on the Transition

5 Application to Biomembranes



Chapter Ten. Interaction of Cadmium and Mercury Ions with Bilayer Lipid Membranes Containing Channels

1 Introduction

2 Materials and Methods

3 Results and Discussion

4 Conclusion


Chapter Eleven. High-Resolution Solid-State NMR of Lipid Membranes

1 Introduction

2 Experimental Considerations

3 Applications

4 Other Applications and New Directions

5 Summary



Chapter Twelve. Thermal Fluctuations of Phospholipid Vesicles Studied by Monte Carlo Simulations

1 Introduction

2 Thermal Fluctuations and Elasticity in Two Dimensions

3 Thermal Fluctuations and Elasticity in Three Dimensions

4 Discussion


Subject Index


Advances in Planar Lipid Bilayers and Liposomes volumes cover a broad range of topics, including main arrangements of the reconstituted system, namely planar lipid bilayers as well as spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field.

Key Features

  • Incorporates contributions from newcomers and established and experienced researchers
  • Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives
  • Serves as an indispensable source of information for new scientists


Chemical Engineers, physical chemists, biologists and biochemists, biochemical engineers


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© Academic Press 2013
Academic Press
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About the Serial Editors

Ales Iglic Serial Editor

Aleš Iglič received his B.Sc. and Ph.D. degrees in physics and M.Sc. degree in biophysics from the Department of Physics, and the Ph.D. degree in electrical engineering from the Faculty of Electrical Engineering, all from the University of Ljubljana. He is a Full Professor and the Head of Laboratory of Biophysics of the Faculty of Electrical Engineering at University of Ljubljana. His main research interests are in electrostatics, mechanics and statistical physics of lipid nanostructures and biological membranes. He is devoted to higher education, basic research in biophysics and close contacts to clinical practice. Prof. Iglič was visiting scientist and professor at Åbo Academy University in Turku (Finland), Friedrich Schiller University in Jena (Germany) and Czech Technical University in Prague (Czech Republic). He established collaborations with researchers from different universities across the Europe, USA and India and was supervisor of many M.Sc., Ph.D. and postdoctoral students from Slovenia, Czech Republic, Poland, Iran, Bulgaria, Germany, India and Israel. Since 2009 is the editor of Elsevier book series »Advances in Planar Lipid Bilayers and Liposomes« (APLBL).

Affiliations and Expertise

Faculty of Electrical Engineering, University of Ljubljana, Slovenia

About the Serial Volume Editors

Julia Genova Serial Volume Editor