
A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics
From the Bench to the Clinic
Description
Key Features
- Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy
- Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials
- Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward
- Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies
Readership
Basic science and clinial researchers, postdocs, fellows, advanced students, and residents focused on the development of stem cell/cell-based therapies
Table of Contents
Part 1 Principles and Concepts
1. What Can We Learn From This Book?
Travis J. Block, David D. Dean and Xiao-Dong Chen
2. Features of Mesenchymal Stem Cells
Stan Gronthos
3. Maintenance and Culture of MSCs
Milos Marinkovic, David D. Dean and Xiao-Dong Chen
4. Manufacturing Mesenchymal Stromal Cell Banks
Jamie Hoover and Patrick J. Hanley
Part 2 Promises and Challenges of MSC-Based Therapies
5. Mesenchymal Stem Cell-Based Therapy of Osteoarthritis: Current Clinical Developments and Future Therapeutic Strategies
Maxime Ruiz, Marie Maumus, Christian Jorgensen and Daniele Noel
6. Mesenchymal Stem Cell Therapy in Graft Versus Host Disease
Shivaprasad Manjappa, Rizwan Romee and Armin Rashidi
7. Systemic Lupus Erythematosus
Dandan Wang and Lingyun Sun
8. Mesenchymal Stem Cell-Based Therapies for Repair and Regeneration of Skin Wounds
Shanmugasundaram Natesan, Randolph Stone, Rodney K. Chan and Robert J. Christy
9. Myocardial Infarction
Natalia Rozwadowska and Maciej Kurpisz
10. Bone Marrow Mesenchymal Stem Cells as a New Therapeutic Approach for Diabetes Mellitus
Joseph Kim, John Z. Q. Luo and Luguang Luo
11. Mesenchymal Stem Cell-Based Therapy for Chronic Kidney Disease
Maria V. Irazabal, LaTonya J. Hickson and Alfonso Eirin
12. Promises and Challenges of MSC-Based Therapies: Parkinson Disease and Parkinsonism
Ashley Aaroe and Claire Henchcliffe
13. Spinal Cord Injury
K. A. Ruppert, S. D. Olson and C. S. Cox
14. Stem Cell-Based Restoration of Salivary Gland Function
Olivia N. Tran, Hanzhou Wang, David D. Dean, Xiao-Dong Chen and Chih-Ko Yeh
15. Tooth and Dental Pulp Regeneration
Bei Li, Chen Xi and Yan Jin
Part 3: Future Perspectives
16. MSCs as Biological Drugs
Thekkeparambil Chandrabose Srijaya, Sandhya Sriram, Noor Hayaty Abu Kasim and Shigeki Sugii
17. Mesenchymal Stem Cell-Derived Products for Tissue Repair and Regeneration
Anand Srinivasan, Michelle Lynn Fults, Peter Supronowicz, Roberto Esquivel and Rogelio Zamilpa
18. Use of MSCs in Antiaging Strategies
Travis J. Block, David D. Dean and Xiao-Dong Chen
19. Regulatory Developments for Nonhematopoietic Stem Cell Therapeutics: Perspectives From the EU, the USA, Japan, China, India, Argentina, and Brazil
Achim Rosemann, Gabriela Bortz and Federico Vasen
Product details
- No. of pages: 544
- Language: English
- Copyright: © Academic Press 2018
- Published: August 31, 2018
- Imprint: Academic Press
- eBook ISBN: 9780128119211
- Paperback ISBN: 9780128119204
About the Editor
Xiao-Dong Chen
Affiliations and Expertise
Ratings and Reviews
Latest reviews
(Total rating for all reviews)
Lily L. Fri Jun 07 2019
A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic
This is a great book! It comprehensively addresses challenges and proposes potential solutions in the current situation of MSC-based therapy by all the authors who bring their own experience and expertise in the fields.
Sy P. Wed Feb 27 2019
A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic
This is a great resource for researchers and clinician alike. As the field expands rapidly many do not appreciate the fundamental methods, characteristics and therapeutic applications for mesenchymal stem cells. This book captures a range of different procedures that have enabled the field to move forward so quickly. Thank you Dr. Chen for putting together such a comprehensive resource.