A Pharmacology Primer

2nd Edition

Theory, Applications, and Methods

Authors: Terry Kenakin
Paperback ISBN: 9780123705990
eBook ISBN: 9780080465302
Imprint: Academic Press
Published Date: 27th October 2006
Page Count: 318

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Description

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.

Key Features

Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

Readership

Researchers in all areas of molecular biology who need the background basics of pharmacology. This list includes pharmaceutical companies, drug disocvery professionals, and researchers in pharmacology, biochemistry, cell biology, and molecular biology. Also can be used for upper-level undergrad textbook.

Table of Contents

What is Pharmacology? How Different Tissues Process Drug Response Drug Receptor Theory Pharmacological Assay Formats: Binding Agonists: The Measurement of Affinity and Efficacy in Functional Assays Orthosteric Drug Antagonism Allosteric Drug Antagonism The Process of Drug Discovery Target- and System-based Strategies for Drug Discovery ‘Hit’ to Drug: Lead Optimization Statistics and Experimental Design Selected Pharmacological Methods Glossary of Pharmacological Terms Appendices: Statistical Tables Mathematical Fitting Functions

Details

No. of pages:
318
Language:
English
Copyright:
© Academic Press 2006
Published:
Imprint:
Academic Press
eBook ISBN:
9780080465302
Paperback ISBN:
9780123705990

About the Author

Terry Kenakin

Terry P. Kenakin is the recipient of the 2008 Poulsson Medal for Pharmacology awarded by the Norwegian Society of Pharmacology for achievements in basic and clinical pharmacology and toxicology. He has also been awarded the 2011 Ariens Award from the Dutch Pharmacological Society and the 2014 Gaddum Memorial Award from the British Pharmacological Society. Having been involved in drug discovery for over 30 years, his interests include the optimal design of drug activity assays systems and quantitative drug receptor theory. He is a member of numerous editorial boards as well as Editor-in-Chief of the Journal of Receptors and Signal Transduction and Current Opinion in Pharmacology. In addition, Dr. Kenakin has authored numerous articles and has also written a number of books on pharmacology.

Affiliations and Expertise

Professor of Pharmacology, The University of North Carolina School Of Medicine, Chapel Hill, NC, USA