The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.

Key Features

*Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition


Researchers in all areas of molecular biology who need the background basics of pharmacology. This list includes pharmaceutical companies, drug disocvery professionals, and researchers in pharmacology, biochemistry, cell biology, and molecular biology. Also can be used for upper-level undergrad textbook.

Table of Contents

What is Pharmacology? How Different Tissues Process Drug Response Drug Receptor Theory Pharmacological Assay Formats: Binding Agonists: The Measurement of Affinity and Efficacy in Functional Assays Orthosteric Drug Antagonism Allosteric Drug Antagonism The Process of Drug Discovery Target- and System-based Strategies for Drug Discovery ‘Hit’ to Drug: Lead Optimization Statistics and Experimental Design Selected Pharmacological Methods Glossary of Pharmacological Terms Appendices: Statistical Tables Mathematical Fitting Functions


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© 2006
Academic Press
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