A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces - 1st Edition - ISBN: 9780444638724

A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

1st Edition

Authors: Ajit Sadana Neeti Sadana Richa Sadana
Paperback ISBN: 9780444638724
Imprint: Elsevier Science
Published Date: 1st September 2018
Page Count: 410
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Description

A Fractal Analysis of the Kinetics of Binding and Dissociation of Different Analytes on Biosensor Surfaces analyses the kinetics of binding and dissociation of different analytes by different biosensor techniques. It demonstrates and compares the different techniques. Emphasis is placed on newer instrumentation techniques such as SPRi (surface plasmon resonance imaging), classical techniques such as SPR (surface plasmon resonance). DNA biosensors, and nanobiosensors. Finally, the capstone chapter includes biosensor economics. All of these factors mentioned above provide under one cover the different aspects of biosensors not considered in detail elsewhere.

Key Features

  • Analyses the kinetics of binding on biosensor surfaces
  • Presents and compares different biosensor techniques
  • Provides insights into the binding and dissociation mechanisms of analytes on biosensor surfaces
  • Links the heterogeneity of biosensor surfaces to dissociation rate coefficients

Readership

Graduate students, researchers and supervisors in academia in biotechnology, biomedical/chemical engineering, biochemistry, chemistry, physics and managers in the industry would find the book useful in helping develop better biosensors. MDs could also find the book useful in helping to diagnose diseases quicker, and more correctly which would lead to a better prognosis

Table of Contents

Chapter 1: INTRODUCTION

Chapter 2: THEORY

Chapter 3: DIFFERENT INSTRUMENTATION TECHNIQUES

(a) Biosensing using porous silicon double-layer interferometers

(b) NMR-based biosensor

(c) Plasmonic-enhanced colorimetric ELISA

(d) Immunchromatographic fluorescent biosensor

(e) Detection of protein-small in an external cavity laser biosensor

(f) Surface acoustic wave biosensor

(g) Molecular beacon biosensor

(h) GC-SPR biosensor

Chapter 4: NANOBIOSENSORS

(a) Self-assembled nanoparticle probes

(b) Label-free immunosensor using gold nanorods

(c) Carbon nanotube based biosensor

(d) Wired enzyme nanoparticle biosensor

(e) Carbon-nanotube based SPR measurements

(f) Rapid, label-free nanobiosensor systems

(g) Ultrasensitive detection on nanowire electrodes

(h) Embedded plasmonic nanomember biosensor

(i) Localized surface plasmon on gold nanoparticles

(j) Quantitative real-time measurements on nanowires in electrolyte solution

Chapter 5: DNA BIOSENSORS

(a) DNA sequence dependent monomer-dimer binding

(b) Quantitative measurement and modeling of ss DNA

(c) Determining the folding and unfolding of G-quadraplex

(d) Kinetic control and hybridization of DNA monolayer surfaces

Chapter 6: CARBOHYDRATE-RECEPTOR INTERACTIONS

(a) Probing the relevance of lectin clustering on biosensor surfaces

(b) High-affinity glycopolymer interactions on biosensor surfaces

 

Chapter 7: SPR BIOSENSORS

(a) Monolayers of 3-mercaptopropyl on SPR biosensors

(b) Noncovalently functionalized SPR immunosensors

(c) Hygromycin B antibody on SPR biosensors

(d) Development of an oligopeptide detection on SPR biosensor

(e) Differential phase SPR biosensor

(f) Screening for GPCR on an SPR biosensor

(g) Biosensor recognition using transport proteins

(h) Fragment screening by SPR

Chapter 8: SPR IMAGING BIOSENSORS

(a) On-chip synthesis of proteins

(b) High-throughput immonophenotyping using SPR imaging

(c) Food allergen profiling using SPR imaging

Chapter 9: DETECTION OF GENERAL COMPOUNDS

(a) Glyphosphate (herbicide)

(b) Antibiotic residues in milk

(c) Combined affinity and catalytic biosensor

(d) Fluorophore-labeled beta-lactamase

(e) Rational design of a novel biosensor for beta-lactamase

(f) In-situ antibody detection and charge discrimination

(g) Stabilized structure switching on solid-phase assays

Details

No. of pages:
410
Language:
English
Copyright:
© Elsevier Science 2019
Published:
Imprint:
Elsevier Science
Paperback ISBN:
9780444638724

About the Author

Ajit Sadana

Dr. Ajit Sadana has recently retired from the University of Mississippi after 34 years. His expertise is in the area of kinetics of binding and dissociation of analytes on biosensor surfaces.

Affiliations and Expertise

Chemical Engineering Department, University of Mississippi, MS, USA

Neeti Sadana

Neeti Sadana is an Assistant Professor of Anaesthesiology at the Department of Anesthesiology, Oklahoma School of Medicine, University of Oklahoma.

Affiliations and Expertise

Department of Anesthesiology, Oklahoma School of Medicine, Oklahoma University, Oklahoma City, USA

Richa Sadana

Richa Sadana has a law degree from the University of Miami, Florida and currently works at New York Life Securities LLC.

Affiliations and Expertise

Financial Services Professional, New York Life Securities LLC, Miami, FL, USA

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