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5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B - 1st Edition - ISBN: 9780444642585, 9780444642592

5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B, Volume 261

1st Edition

Serial Volume Editors: Giuseppe Giovanni Philippe De Deurwaerdere
Hardcover ISBN: 9780444642585
eBook ISBN: 9780444642592
Imprint: Elsevier
Published Date: 24th March 2021
Page Count: 476
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Table of Contents

Part 1: Serotonin in the CNS
1. The multiple facets of serotonergic modulation on brain functions
Giuseppe Di Giovanni
2. Anatomical and neurochemical organization of the serotonergic system in the mammalian brain
Harry Steinbusch
3. 5-HT2A/2C Receptors in the Brain
Cristiano Bombardi

Part 2 : Serotonin-dopamine interactions
4. Electrophysiological and neurochemical bases for an interaction of serotonin on central dopaminergic neurons
Giuseppe Di Giovanni
5. The complex nature of serotonin-dopamine neurons interaction in primate model of Parkinson’s disease
Véronique Sgambato
6. The status of serotonergic system in presymptomatic and symptomatic stages of Huntington disease and corresponding animal models
Anthony Hannan
7. Serotonin–dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias
Manolo Carta
8. The serotonergic agent L-DOPA in the treatment of Parkinson’s disease
Marios Politis

Part 3: Serotonin-Glutamate interaction
9. Cortical influences of serotonin on pyramidal cells
Gerard Joseph Marek
10. The interaction of serotonin with noradrenergic, dopaminergic, cholinergic, and opioid systems in Alzheimer's disease
Goran Simic
11. Serotonergic controls upon the glutamatergic neurons of the subthalamic nucleus
Luisa Ugedo


The Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Key Features

  • Covers all key aspects of current research on 5-HT interaction with other neurotransmitters
  • Provides extensively referenced chapters, thus giving readers a comprehensive list of resources on topics covered
  • Includes comprehensive and in-depth background information written in a clear form that is accessible to both specialists and non-specialists


Researchers, academics and all others interested in or involved in study of 5-HT interaction with other neurotransmitters


No. of pages:
© Elsevier 2021
24th March 2021
Hardcover ISBN:
eBook ISBN:

Ratings and Reviews

About the Serial Volume Editors

Giuseppe Giovanni

Prof. Giuseppe Di Giovanni received his Ph.D. in Neuroscience from the University of Chieti, Italy and was a postdoctoral fellow at Yale University, USA. Previously Senior Lecturer of Human Physiology at the Faculty of Medicine and Surgery, University of Palermo, and Associate Professor at the University of Malta, from 2013 he is Professor of Human Physiology at the Medical School of the University of Malta and from 2018 Honorary Professor at Cardiff University, UK. His research focuses on understanding the pathophysiology of monoaminergic systems using electrophysiological and neurochemical approach. He has published more than 120 peer-reviewed papers, edited 7 books and 6 special issues of various journals.

Affiliations and Expertise

University of Malta, Malta

Philippe De Deurwaerdere

Professor Philippe De Deurwaerdère, Centre National de la Recherche Scientifique Bordeaux Cedex France

Affiliations and Expertise

Centre National de la Recherche Scientifique, France