5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B

5-HT Interaction with Other Neurotransmitters: Experimental Evidence and Therapeutic Relevance Part B

1st Edition - March 24, 2021
This is the Latest Edition
  • Editors: Giuseppe Giovanni, Philippe De Deurwaerdere
  • Hardcover ISBN: 9780444642585
  • eBook ISBN: 9780444642592

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The Progress in Brain Research series highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Key Features

  • Covers all key aspects of current research on 5-HT interaction with other neurotransmitters
  • Provides extensively referenced chapters, thus giving readers a comprehensive list of resources on topics covered
  • Includes comprehensive and in-depth background information written in a clear form that is accessible to both specialists and non-specialists


Researchers, academics and all others interested in or involved in study of 5-HT interaction with other neurotransmitters

Table of Contents

  • Part 1: Serotonin in the CNS
    1. The multiple facets of serotonergic modulation on brain functions
    Giuseppe Di Giovanni
    2. Anatomical and neurochemical organization of the serotonergic system in the mammalian brain
    Harry Steinbusch
    3. 5-HT2A/2C Receptors in the Brain
    Cristiano Bombardi

    Part 2 : Serotonin-dopamine interactions
    4. Electrophysiological and neurochemical bases for an interaction of serotonin on central dopaminergic neurons
    Giuseppe Di Giovanni
    5. The complex nature of serotonin-dopamine neurons interaction in primate model of Parkinson’s disease
    Véronique Sgambato
    6. The status of serotonergic system in presymptomatic and symptomatic stages of Huntington disease and corresponding animal models
    Anthony Hannan
    7. Serotonin–dopamine interaction in the induction and maintenance of L-DOPA-induced dyskinesias
    Manolo Carta
    8. The serotonergic agent L-DOPA in the treatment of Parkinson’s disease
    Marios Politis

    Part 3: Serotonin-Glutamate interaction
    9. Cortical influences of serotonin on pyramidal cells
    Gerard Joseph Marek
    10. The interaction of serotonin with noradrenergic, dopaminergic, cholinergic, and opioid systems in Alzheimer's disease
    Goran Simic
    11. Serotonergic controls upon the glutamatergic neurons of the subthalamic nucleus
    Luisa Ugedo

Product details

  • No. of pages: 476
  • Language: English
  • Copyright: © Elsevier 2021
  • Published: March 24, 2021
  • Imprint: Elsevier
  • Hardcover ISBN: 9780444642585
  • eBook ISBN: 9780444642592

About the Serial Volume Editors

Giuseppe Giovanni

Prof. Giuseppe Di Giovanni received his Ph.D. in Neuroscience from the University of Chieti, Italy and was a postdoctoral fellow at Yale University, USA. Previously Senior Lecturer of Human Physiology at the Faculty of Medicine and Surgery, University of Palermo, and Associate Professor at the University of Malta, from 2013 he is Professor of Human Physiology at the Medical School of the University of Malta and from 2018 Honorary Professor at Cardiff University, UK. His research focuses on understanding the pathophysiology of monoaminergic systems using electrophysiological and neurochemical approach. He has published more than 120 peer-reviewed papers, edited 7 books and 6 special issues of various journals.

Affiliations and Expertise

University of Malta, Malta

Philippe De Deurwaerdere

Professor Philippe De Deurwaerdère, Centre National de la Recherche Scientifique Bordeaux Cedex France

Affiliations and Expertise

Centre National de la Recherche Scientifique, France