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| CHEMOKINES, 287
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 To order this title, and for more information, click here
Richard Horuk, Berlex Biosciences, Richmond, California, U.S.A.
John Abelson, California Institute of Technology, Division of Biology, Pasadena, U.S.A.
Melvin Simon, California Institute of Technology, Division of Biology, Pasadena, USA
Description
Chemokines are major mediators of immune cells and are involved in a wide range of proinflammatory human diseases, including rheumatoid
arthritis, multiple sclerosis, and organ transplant rejection. It has recently been discovered that their receptors are involved in HIV
infection. The characterization of these molecules and their receptors is thus of primary importance in understanding a number of human
diseases and infections. This volume and its companion Volume 288 on Chemokine Receptors provide comprehensive experimental
protocols used in this field of research.
Audience
Biochemists, molecular biologists, immunologists, cell biologists, pharmacologists, and biomedical researchers.
Contents
C-X-C Chemokines:
R. Horuk, D. Reilly, and D. Yansura, Expression, Purification, and Characterization of Escherichia
coli Derived Recombinant Human Melanoma Growth Stimulating Activity.A. Wuyts, P. Proost,G. Froyen, A. Haelens, A. Billiau, G.
Opdenakker, and J. Van Damme, Purification and Identification of Human and Mouse Granulocyte Chemotactic Protein-2 Isoforms.P.E.
Dawson, Synthesis of Chemokines by Native Chemical Ligation.W.J. Fairbrother and H.B. Lowman, Molecular Approaches to Structure-Function
Analysis of Interleukin-8.J. Hesselgesser and R. Horuk, Alanine Scan Mutagenesis of Chemokines.D. Baly, U. Gibson, D. Allison,
and L. DeForge, Biological Assays for C-X-C Chemokines.K. Rajarathnam, C.M. Kay, I. Clark-Lewis, and B.D. Sykes, Characterization
of Quaternary Structure of Interleukin-8 and Functional Implications.
C-C and C Chemokines:
J. Van Damme, S. Struyf, A. Wuyts,
G. Opdenakker, P. Proost, P. Allavena, S. Sozzani, and A. Mantovani, Isolation of Human Monocyte Chemotactic Proteins and Study of
their Producer and Responder Cells by Immunotests and Bioassays.A.-M. Buckle, S. Craig, and L.G. Czaplewski, Assays for Macrophage
Inflammatory Proteins.P.J. Nelson, J.M. Pattison, and A.M. Krensky, Gene Expression of RANTES.A.M. Krensky and P.J. Nelson,
Expression of Chemokine RANTES and Production of Monoclonal Antibodies.R.C. Newton and K. Vaddi, Biological Responses to C-C
Chemokines.D.N. Cook, Gene Targeting Strategies to Study Chemokine Function in Vivo.J.A. Hedrick and A. Zlotnik,
Lymphotactin: A New Class of Chemokine.J.M. Schrider, Isolation and Purification of Neutrophil Activating Peptide 4: A Chemokine
Missing Two Cysteines.
Other Methods:
I. Clark-Lewis, L. Vo, P. Owen, and J. Anderson, Chemical Synthesis Purification
and Folding of C-X-C and C-C Chemokines.J.B. Smith and H.R. Herschmann, Identification of Inflammatory Mediators by Screening
for Glucocorticoid-Attenuated Response Genes.D.D. Taub, M.L. Key, D.L. Longo, and W.J. Murphy, Chemokine-Induced Human Lymphocyte
Infiltration and Engraftment in huPBL-SCID Mice.D.A. Barnes and H.D. Perez, HighThroughput Screening for Identification of RANTES
Chemokine Expression Inhibitors.S.A. Lira, M.E. Fuentes, R.M. Strieter, and S.K. Durham, Transgenic Methods to Study Chemokine
Function in Lung and Central Nervous System.R.M. Ransohoff, M Tani, A.R. Glabinski, A. Chernosky, K. Krivacic, J.W. Peterson, H.-F.
Chien, and B.D. Trapp, Chemokines and Chemokine Receptors in Model Neurological Pathologies: Molecular and Immunocytochemical Approaches.
R.E. Offord, H.F. Gaertner, T.N.C. Wells, andA.E.I. Proudfoot, Synthesis and Evaluation of Fluorescent Chemokines Labeled at the
Amino Terminal.G.S.V. Kuschert, R.E. Hubbard, C.A. Power, T.N.C. Wells, and A.J. Hoogewerf, Solid-Phase Binding Assay to Study
Interaction of Chemokines with Glycosaminoglycans.M. Conklyn and H.J. Showell, Biological Activity of C-X-C and C-C Chemokines
in Leukocyte Subpopulations in Human Whole Blood.
Author Index.
Subject Index.
| Bibliographic details |
Hardbound, 421 pages, publication date: SEP-1997
ISBN-13: 978-0-12-182188-3
ISBN-10: 0-12-182188-9
Imprint: ACADEMIC PRESS
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| Price and Ordering |
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EUR 128
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Last update: 27 Sep 2008
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