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ADVANCES IN HADRONTHERAPY
Advances in HadrontherapyProceedings of the International Week on Hadrontherapy, European Scientific Institute, Archamps, France, 20-24 November 1995 and of the Second International Symposium on Hadrontherapy, PSI and CERN, Switzerland, 9-13 September 1996

Edited by
U. Amaldi, CERN, European Laboratory for Particle Physics, Geneva, Switzerland and University of Milan, II Science Faculty, Como, Italy
B. Larsson, Institute for Medical Radiobiology of the University of Zürich, Switzerland and The Paul Scherrer Institute, Zürich, Switzerland
Y. Lemoigne, European Scientific Institute, French Geneva Campus, Archamps, France

Included in series
International Congress, 1144

Description
This book offers the reader a complete view of the general field of tumor therapy using hadrons, both neutral and charged.

Contents
Note from the Editors (U. Amaldi, B. Larsson, Y. Lemoigne). List of contributors. Foreword to the Second International Symposium on Hadrontherapy (R.R. Wilson).

Cancer and hadrons: a scientific, socioeconomic and ethical outlook.
Molecular and cellular responses to radiotherapy (J. Yarnold). Hadrontherapy - do we need it? (H.D. Kogelnik). Basis for interest in proton beam radiation therapy (H.D. Suit, M. Krengli).What kind of radiobiology ahould be done at the hadrontherapy centre? (G. Kraft et al.). Cost-benefit considerations of hadrontherapy (G. Gademann). Clinical trials and ethical issues in cancer research (J. Bernier, D. Lacombe, F. Meunier).

Clinical experience.
Clinical programs: a review of past and existing hadron protocols (J.R. Castro). Clinical experience with proton beam therapy at MGH, MEEI and HCL: skull base sarcoma and uveal melanoma (M. Krengli, J.E. Munzenrider, H.D. Suit). Clinical experience with proton beam therapy at MGH and HCL: proton radiation oncology group trials (H.D. Suit, M. Krengli, J.E. Munzenrider). Palatal salivary gland tumours treated with neutron therapy: should the bite block be built up to reduce the air gap? (C. Stannard et al.). Treatment precision with proton beams: clinical experience and potential new indications (R. Miralbell).

Accelerators and facilities.
Accelerations for hadrontherapy (P. Mandrillon). Overview of technical and operational essentials for a hadrontherapy facility (J.M. Slater et al.). Hyogo Hadrontherapy Center Project (A. Itano et al.). The Tera Foundation and its projects in oncological hadrontherapy (U. Amaldi, S. Rossi). The TOP-LINAC for the protontherapy project of the Italian National Institute of Health (ISS) (S. Frullani et al.). The AUSTRON project: in-depth study of the clinical aspect of AUSTRON (M. Regler, Th. Auberger). New proton facility at the National Cancer Center Hospital East: Kashiwa project (S. Murayama et al). The technology of hadrontherapy: the context within which technical choices are made (M. Goitein). The quality control program for the NAC neutron therapy facility (A.N. Schreuder, D.T.L. Jones, J.E. Symons).

Techniques of hadrontherapy.
Patient assessment, treatment planning and dose delivery (A. Lomax, M. Goitein). Three years' experience with the NAC proton therapy patient positioning system (A.N. Schreuder et al.). Design approach for the highly accurate patient positioning system for NPTC (J.B. Flanz et al.). real-time tracking of tumor positions for precision irradiation (S. Kirsch et al.). Simple range-measurement method using visible scintillation light (A. Fukumura et al.). New methods for patient alignment (G. Baroni et al.). A small ionization chamber for dose distribution measurement in a clinical proton beam (A.N. Schreuder, D.T.L. Jones, A. Kiefer). Routine three-dimensional dosimetry of hadron beams (R. Cirio et al.). VLSI electronics as readout for hadron dosimeters (G.C. Bonazolla et al.). Treatment planning of proton beams using the GEANT Monte Carlo (R. Ragona, V. Rolano, A. Solano). A detection system for the verification of three-dimentional dose distributions (C. Brusasco, D. Schardt, B. Voss). Fragmentation of 270 A. MeV carbon ions in water (M. Golovkov et al.). Attenuation of therapeutic heavy-ion beams in various thick targets due to projectile fragmentation (A. Fukumura et al.). Real and simulated data comparative studies for proton energy loss (S. Garelli, S. Giordano, S. Squarcia). Simulation of fragmentation of carbon ions (F. Marchetto). Imaging of 11C distribution in patients induced by autoactivation of 12C beams (T. Tomitani et al.). Results of a small scale dosimetry comparison with carbon-12 ions ar GSI Darmstadt(G.H. Hartmann et al.). Therapy planning for heavy-ion irradiation (M. Krämer, O. Jäkel). Molecular radiotherapy with 211At (R. Weinreich).

Radiobiology.
Radiobiology of heavily charged particles (G. Kraft). RBE for inactivation of tumoural and normal cell lines of human origin irradiated with low energy protons (M. Belli et al.). RBE of the 200 MeV proton beam produced at the National Accelerator Centre of Faure (South Africa) for late lung tolerance in mice after single- and fractionated-irradiation (preliminary results) (J. Gueulette et al.). Biological effectiveness of protons on mammalian cells (M. Dellert et al.). Experimental biophysical investigations in a 178.9 MeV proton beam (R. Becker et al.). Do different ways of beam modulation cause different proton RBE values? (H. Pagnetti, T. Schmitz). Deviations of survival curves from the LQ-shape and cumulative effect in fractionation (M. Lokajiček, J. Polák, K. Prokeš). Microdosimetric aspects of proton RBE (M.F. Lomanov).

Generic technologies for the present and future of hadrontherapy.
Advances in computing and trends in bioinformatics (P. Zanella). The World-Wide-Web; past, present and future and its application to medicine (D.M. Sendall). The RITA project (M. Ferraris, P. Risso, S. Squarcia). Advances in large and precise mechanical structures (G. Bachy). Development and applications of electronic gas detectors (F. Sauli).

Appendix 1, Appendix 2, Index of authors. Keyword index.


Bibliographic & ordering Information
Hardbound, 572 pages, publication date: DEC-1997
ISBN-13: 978-0-444-82782-1
ISBN-10: 0-444-82782-X
Imprint: EXCERPTA MEDICA
Price: Order form
USD 226
EUR 226
GBP 150.50

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Last update: 10 Jul 2008
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