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BONE FORMATION AND REPAIR
Bone Formation and RepairProceedings of the International Symposium on Formation and Repair of Mineralized Extracellular Matrix, Hong Kong, 18-19 October 1996

Edited by
A.M. Rabie, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, Hong Kong
M.R. Urist, University of California, Los Angeles (UCLA), Bone Research Laboratory, Rehabilitation Center, Los Angeles, CA, USA

Included in series
International Congress, 1139

Description
This book deals with research into the molecular biology and biochemistry of the extracellular matrix of mineralized tissues. Special emphasis is given to aspects of research that ultimately lead to the resolution of diseases afflicting man. This volume presents concepts of bone matrix structure and composition, evaluation of BMP expression and biogenesis, BMP in bone and dentine, angiogenesis and its role in wound healing. A dialogue in presentations and discussions highlights the clinical applications of BMP and composite bone grafts in modern reconstructive, implant and orthopedic surgery.

This book is directed at biochemists and molecular biologists in the area of mineralized tissues such as bone and dentine. It also caters for clinicians in Dentistry such as dental implant surgery, oral and maxillofacial surgery, periodontists and orthodontists.

Contents


Bone Induction and Role of Angiogenesis in the Healing.
Bone as a tissue (A. Veis). Bone morphogenetic proteins. Part 1 (M.R. Urist). Bone morphogenetic proteins. Part 2 (M.R. Urist). BMP expression and bone biogenesis (A.M. Rabie, M.R. Urist). Composite grafts in alveolar ridge augmentation for implants (A.M. Rabie, M.B. Comfort). Effect of TGF-β1 on enhancement of rate and quantity of osseointegration for dental implants: a preliminary study (Y.L. Huang et al.). Study of interface bone induced between allogeneic cranial bone blocks used as onlay grafts in rabbits and rhesus monkeys (M. Sharawy et al.). Bone grafting procedures in the maxillofacial region: a clinical perspective (N. Samman, L.K. Cheung, H. Tideman). Bone repair in orthopaedic surgery (W.M. Tang, K.Y. Chiu, S.P. Chow). Mouse models for the study of fracture repair (K.M.C. Cheung, K.S.E. Cheah). Molecular and biochemical advances in the field of clinical bone induction (A.M. Rabie). The role of macrophages in the control of angiogenesis in wound repair: nitric oxide (NO), angiogenesis inhibitors and tumor suppresser genes (S.J. Leibovich et al.). Vascular anatomy of the temporalis muscle flap and its surgical implication (L.K. Cheung, N. Samman, H. Tideman).

Regulation of Extracellular Matrix Biosynthesis and Extracellular Matrix Macro-molecules.
Dentin matrix proteins (A. George). The distribution of serum proteins in dental hard tissues (Y. Takagi). The unique nature of the temporomandibular joint metabolism. The clinical implications (T.M. Graber). Phosphorylation of matrix vesicle components - dependent on alkaline phosphatase? (P.J. Hung, D.K.Y. Shum, T.R.C. Boyde). Electrophoretic studies on matrix vesicles from rabbit growth plate cartilage (W.C.H. Leung, D.K.Y. Shum, T.R.C. Boyde). Bioprosthetic heart valve calcification: pathophysiology and prevention (C.L. Webb et al.). Urinary glycosaminoglycans and crystallization of urinary calcium oxalate (D.K.Y. Shum, M.D.I. Gohel). A study of Zeng-Gu-San, a new Chinese traditional herb for periodontitis, and observation of its clinical effects (F.M. Wen et al.).

Abstract Session.
Bone as a tissue: structure, growth and repair (A. Veis). Genotype-phenotype relationships in the growth plate (K.S.E. Cheah et al.). Resistance to E. coli heart-stable enterotoxin Sta and skeletal abnormalities in mice lacking the cyclic GMP-dependent protein kinase II gene (R. Fässler et al.). Characterization of the dentin matrix proteins and its role in dentin mineralization (A. George). The distribution of serum proteins in dental hard tissues (Y. Takagi). The characteristics of microsomal casein kinase II in osteoblastic cells - its role in the phosphorylation of matrix protein (W.C. Bing). The role of macrophages in the control of angiogenesis in wound repair: nitric oxide (NO), angiogenesis inhibitors and tumor suppressor genes (S.L. Leibovich et al.). The vascular anatomy of temporalis muscle flap and its surgical implication (L.K. Cheung, N. Samman, H. Tideman). Urinary glycosaminoglycans and crystallization of urinary calcium oxalate (D.K.Y. Shum, M.D.I. Gohel). Orthodontic forces and periodontal response (E.H.K. Yen). Effect of TGF-β1 on enhancement of rate and quantity of osseointegration for dental implant(Y.L. Huang, R.A. Smith, R. Derynck). Study of interface bone induced between allogeneic cranial bone blocks used as onlay grafts in rabbits and rhesus monkeys (M. Sharawy). Molecular and biochemical advances in the field of clinical bone induction (A.M. Rabie). Unique features of the human temporomandibular joint (T.M. Graber). Bioprosthetic heart valve calcification: pathophysiology and prevention (C.L. Webb et al.). High resolution SSCP analysis by ethidium bromide staining using formamide as a denaturant (T. Xie, S.-L. Ho). Use of coral as a bone graft substitute for reconstruction of mandibles - Experimental studies and clinical applications (R.-S. Zeng, C.-N. Ren, Y.-H. Zeng). Functional reconstruction of the lower and upper jaws after segmental resection (H. Tideman). Free fibular osteocutaneous flap for mandibular reconstruction (W.I. Wei et al.). Bone repair in orthopaedic surgery (K.Y. Chiu, W.M. Tang, S.P. Chow). Bone grafting procedures in the maxillofacial region: the clinical perspective (N. Samman, L.K. Cheung, H. Tideman). Composites of BMP and biomaterials for bone reconstruction (T. Kawai). A study of Zeng-Gu-San and observation of its clinical effects on alveolar bone (M.-W. Fan et al). Experimental and clinical studies on reimplantation of frozen autogenous mandible (G.-Z. Zhang et al.). Bone induction: a goal in sight (A.M. Rabie). Alveolar ridge augmentation for implants (M.B. Comfort). Phosphorylation of MV components - dependent on alkaline phosphatase? (P.J. Hung, D.K.Y. Shum, T.R.C. Boyde). Identification and characterization of multiple osmotic response elements in the promotor of aldose reducatase gene (B.C.B. Ko, S.M. Chung). Mice lacking collagen X: implications for function during bone formation (K.M. Kwan et al.). Characterization of a mutation that causes sorbitol dehydrogenase deficiency in mouse (F.K. Lee, S.K. Chung, S.S.M. Chung). Dissecting distinct cis-acting elements regulating human a1 (II) collagen gene expression (K.K.H. Leung et al.). Electrophoretic studies on matrix vesicles from rabbit growth plate cartilage (W.H.C. Leung, D.K.Y. Shum, T.R.C. Boyde). Bacteria-Candida interactions in the oral cavity: in vitro evaluations (R.G. Nair).The sry-related gene sox-9 encodes a transcriptinal activator and is co-expressed with the α1 (II) collagen (Col2al) gene in skeletal tissues during mouse development (L.J. Ng et al.). Relative cell surface hydrophobicity of Candida parapsilosis and Candida albicans (G.J. Panagoda, L.P. Samaranayake). Transgenic mouse model of human chondrodysplasia (C.L. So et al.). Biochemical differences between endochondral bone and intramembranous bone matrix (A. Twitty, A.M. Rabie, D.K.Y. Shum). Abnormal condrocyte differentiation in chimeric mice containing COL2A1-directed SV40 T-antigen expressing cells (A.W.K. Wai, P.P.L. Tam, K.S.E. Cheah).

Index of authors.


Bibliographic & ordering Information
Hardbound, 232 pages, publication date: DEC-1997
ISBN-13: 978-0-444-82652-7
ISBN-10: 0-444-82652-1
Imprint: EXCERPTA MEDICA
Price: Order form
USD 155
GBP 103.50
EUR 155

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Last update: 16 Jul 2008
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