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| ADVANCES IN ENZYME REGULATION, VOLUME 42, 42
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 To order this title, and for more information, click here
Edited By
George Weber, Indiana University School of Medicine, Indianapolis, USA
Included in series
Advances in Enzyme Regulation, 42
Description
Volume 42 lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies.
This volume contains papers of 25 outstanding scientists working at the cutting edge of metabolic regulation. Much of the volume focuses
on novel aspects of signal transduction with an emphasis on nuclear expression.
One of the highlights of this volume is the Special
Symposium Lecture. This was given for 15 years by Sir Hans A. Krebs who passed away 20 years ago. It was now given by Professor Sir Hans
L. Kornberg, University Professor at Boston University.
These volumes continue to be a source of information and inspiration and
a laboratory and advanced teaching companion. The immediate and long-range significance of these cutting-edge presentations of these
novel topics should be immediately clear to the reader.
Contents
Foreword. List of Participants. Emery-dreifuss muscular dystrophy, nuclear cell signaling and chromatin remodeling (N.M. Maraldi, S. Squarzoni et al.). In situ detection of phospholipid and phosphoinositide metabolism (G.D. Prestwich, R. Chen et al.). Regulating
the mammalian genome: the role of nuclear architecture (R. Berezney). Co-operation of phosphatidylinositol transfer protein with phosphoinositide
3-kinase γ in vitro (G.S. Kular, A. Chaudhary et al.). Gene expression profiling in RAS oncogene-transformed cell lines
and in solid tumors using subtractive suppression hybridization and cDNA arrays (C. Sers, O.I. Tchernitsa et al.). Reciprocal
regulation: recognition of pattern of gene expression in cancer cells (G. Weber). Detection of apoptosis in tumors using magnetic resonance
imaging and spectroscopy (K.M. Brindle). Mitochondria and ceramide: intertwined roles in regulation of apoptosis (H. Birbes, S. El Bawab et al.). The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents
that improve tumor oxygenation (M. Stubbs, S.P. Robinson et al.). Overexpression of protein disulfide isomerase-like protein
in a mouse leukemia L1210 cell line selected for resistance to 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone, a ribonucleotide
reductase inhibitor (T.R. Crenshaw, J.G. Cory). Structure-based development of cathepsin L inhibitors and therapeutic applications for
prevention of cancer metastasis and cancer-induced osteoporosis (N. Katunuma, H. Tsuge et al.). The atypical PKC scaffold protein
P62 is a novel target for anti-inflammatory and anti-cancer therapies (J. Moscat, M.T. Diaz-Meco). Inositides in the nucleus: regulation
of nuclear PI-PLC-β1 (L. Cocco, A.M. Martelli et al.). Regulation of phospholipase C-γ1 by protein kinase A-dependent
phosphorylation (Sun Sik Bae, Jang Hyun Choi et al.). DGK and nuclear signaling nuclear diacylglycerol kinases in IIC9 cells
(L. Bregoli, B. Tu-Sekine et al.). The functional efficiency of lipogenic and cholesterogenic gene expression in normal mice
and in mice lacking the peroxisomal proliferator-activated receptor-alpha (PPARα) (G.F. Gibbons, D. Patel et al.). Regulation
of the activity of the pyruvate dehydrogenase complex (R.A. Harris, M.M. Bowker-Kinley et al.). Regulation of the intracellular
localization of phosphoinositide-specific phospholipase cδ1 (H. Yagisawa, M. Yamaga et al.). Lysosomal cathepsins:
structure, role in antigen processing and presentation, and cancer (V. Turk, B. Turk et al.). Application of 15N
to the study of hepatic nitrogen metabolism (J.T. Brosnan, M.E. Brosnan et al.). Regulation of glycolysis by Raf protein serine/threonine
kinases (V. Le Mellay, R. Houben et al.). Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue
in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex (D.R. Mole, C.W. Pugh et al.).
If at first you don't succeed...fructose utilization by Escherichia coli (H. Kornberg). Author Index. Subject Index.
Bibliographic & ordering Information
Hardbound, 426 pages, publication date: SEP-2002
ISBN-13: 978-0-08-044123-8
ISBN-10: 0-08-044123-8
Imprint: PERGAMON
Price: Order form
EUR 795
GBP 530
USD 901
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Last update: 29 Aug 2008
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