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| PRINCIPLES OF CELLULAR ENGINEERING
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Understanding the Biomolecular Interface
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Edited By
Michael King, University of Rochester, New York, USA
Description
This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at
the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact
with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular
system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering
concepts and tools may be effectively applied to complex systems in biomedicine.
Audience
Biomedical engineers, cell and molecular biologists, and graduate students in cell and tissue engineering
Contents
Partial Contents:
PART I. NEUTROPHIL ADHESION
Adhesion of flowing neutrophils to model vessel surfaces
Bond formation during cell compression
A flow chamber for capillary networks
Membrane dynamics during neutrophil recruitment
Hydrodynamic recruitment of cells to reactive surfaces
PART II: CELL-SUBSTRATE ADHESION
Cell tensegrity models and cell-substrate interactions
Use of hydrodynamic shear stress to analyze
cell adhesion
Traction forces exerted by endothelial cells
Control of endothelial cell adhesion by mechanotransmission
PART III. ENGINEERED
BIOMIMETIC SURFACES
Realistic atomistic modeling of protein adsorption to ceramic biomaterials
Cell responses to micro- and nano-topography
| Bibliographic details |
Hardbound, 320 pages, publication date: DEC-2005
ISBN-13: 978-0-12-369392-1
ISBN-10: 0-12-369392-6
Imprint: ACADEMIC PRESS
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| Price and Ordering |
Price:
USD 120
EUR 93.95
GBP 80
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Last update: 5 Sep 2009
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