Edited by
Kim Barrett, Professor of Medicine and Vice-Chair for Research, Department of Medicine, University of California, San Diego, San Diego, California, U.S.A.
Fayez Ghishan, Horace W. Steele Endowed Chair in Pediatric Research Head, Department of Pediatrics and
Director, Steele Children's Research Center,
Department of Pediatrics, University of Arizona Health Sciences Center, Tucson, Arizona, U.S.A.
Juanita Merchant, Professor of Internal Medicine and
Integrative and Molecular Physiology, University of Michigan, Ann Arbor, Michigan, U.S.A.
Hamid Said, Professor of Medicine, Physiology and Biophysics, Departments of Medicine and Physiology/Biophysics, University of California School of Medicine, Irvine, California, U.S.A.
Jackie Wood, Professor of Physiology and Cell Biology and Internal Medicine, College of Medicine,
The Ohio State University, Columbus, Ohio, U.S.A.
Editor-in-Chief:
Leonard Johnson, Vice Chancellor for Research and Thomas A. Gerwin Professor of Physiology, University of Tennessee, Memphis, USA
Description
FROM THE PREFACE:
The original purpose of the First Edition of
Physiology of the Gastrointestinal Tract—to collect
in one set of volumes the most current and comprehensive knowledge in our field—was also the driving force for the Fourth Edition.
The explosion of information at the cellular level, made possible in part by the continued emergence of powerful molecular and cellular
techniques, has resulted in a greater degree of revision than that of any other edition. The first section, now titled "Basic Cell Physiology
and Growth of the Gl Tract" contains numerous new chapters on topics such as transcriptional regulation, signaling networks in development,
apoptosis, and mechanisms in malignancies. Most of the chapters in this section were edited by Juanita L. Merchant. Section II has been
renamed "Neural Gastroenterology and Motility" and has been expanded from seven chapters with rather classic titles to more than twenty
chapters encompassing not only the movement of the various parts of the digestive tract but also cell physiology, neural regulation,
stress, and the regulation of food intake. Almost all of the chapters were recruited and edited by Jackie D. Wood. The third section
is entirely new and contains chapters on "Immunology and Inflammation" which were edited by Kim E. Barrett. The fourth section on the
"Physiology of Secretion" consists of chapters with familiar titles, but with completely updated information to reflect the advances
in our understanding of the cellular processes involved in secretion. The last section on "Digestion and Absorption" contains new chapters
on the intestinal barrier, protein sorting and ion channels along with those focusing on the uptake of specific nutrients. These chapters
were recruited and edited by Hamid M. Said and Fayez K. Ghishan.
Audience:
Clinical gastroenterologists, Grad-level lecturer, American College of Gastroenterology members, Internists, and Physiologists
