Description Circadian rhythm sleep disorders are caused by a mismatch between the sleep - wake pattern and circadian phase. Sleep at the circadian
high is impaired, while alertness is reduced during wakefulness. This issue discusses biological timekeeping, consequences of circadian
disruption in animal models, influence of circadian system on disease severity, effect of light on circadian physiology, melatonin, non-24-hour
disorder, irregular sleep-wake disorder, advanced sleep phase, delayed sleep phase, jet lag, shift work, circadian disruption and psychiatric
disorders, and winter depression.