Description There are 300,000 cases of hospital-acquired pneumonia (HAP) annually, and it carries an associated mortality of 30% to 70%. General
risk factors for developing HAP include age more than 70 years, serious comorbidities, malnutrition, impaired consciousness, prolonged
hospitalization, and chronic obstructive pulmonary diseases. HAP is the most common infection occurring in patients requiring care in
an intensive care unit (ICU). This issue provides a comprehensive and updated review of pneumonia in the hospital setting.
Contents 1. Community Acquired Pneumonia and Sepsis (Beutz and Abraham) 2. The Systemic Response to Lung Infection (Deng and Standiford) 3.
Pneumonia in the Solid Organ Transplant Patient (Chakinala and Trulock) 4. Non-Resolving Pneumonia (Weyers) 5. Antimicrobial
Treatment of Hospital-Acquired Pneumonia (Fagon and Chastre) 6. Antimicrobial Treatment of Community-Acquired Pneumonia (Restrpo
and Anzueto) 7. Prevention of Pneumonia in the Hospital Setting (Osmon and Kollef) 8. Antimicrobial Resistance and Treatment of
Community Acquired Pneumonia (Mandell) 9. Etiology of Community-Acquired Pneumonia (Apisarthanarak and Mundy) 10. Mechanisms
of Resistance of Bacteria Causing Ventilator-Associated Pneumonia (Szabo, Silveira, Fujitani and Paterson) 11. Etiology of Ventilator-Associated
Pneumonia (Rello, Diaz and Rodriguez) 12. Preventing Pneumonia: The Role for Pneumococal and Influenza Vaccines (Shorr) 13. Genetic
Susceptibility to Pneumonia (Waterer and Wunderink) 14. Microbiologic Diagnosis of Ventilator Associated Pneumonia (Baughman) 15.
Pulmoary Host Defenses and Factors Predisposting to Lung Infection (Mason and Nelson) 16. Pathophysiology of Pneumonia (Alcon, Fabregas
and Torres) 17. Acute Lung Injury and Bacterial Infection (Dreyfuss and Ricard)
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