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 | TIETZ TEXTBOOK OF CLINICAL CHEMISTRY AND MOLECULAR DIAGNOSTICS
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Fourth Edition
By
Carl Burtis, PhD, Chief, Clinical Chemistry, Health Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT
Edward Ashwood, MD, Professor of Pathology, University of Utah, and Laboratory Director, ARUP Laboratories, Salt Lake City, UT
David Bruns, MD, Professor of Pathology, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia, Charlottesville, VA, and Editor, Clinical Chemistry, Washington, DC
Description
Bridging the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and
disease, this classic resource provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory
tests. Its up-to-date, encyclopedic coverage of the field defines analytical criteria for the medical usefulness of laboratory procedures,
introduces new approaches for establishing reference ranges, describes variables that affect tests and results, examines modern analytical
tools and their impact on lab management and costs, and demonstrates the applications of statistical methods.
Contents
Section 1 Laboratory Principles
1. Introduction to Principles of Laboratory Analyses and Safety 2. Specimen Collection
and Processing
Section 2 Analytical Techniques and Instrumentation
3. Optical Techniques 4. Electrochemistry
and Chemical Sensors 5. Electrophoresis 6. Chromatography 7. Mass Spectometry 8. Principles of Clinical Enzymology 9.
Principles of Immunochemical Techniques 10. Nanotechnology and Microfabrication 11. Automation in the Clinical Laboratory 12.
Point-of-Care Testing
Section 3 Principles of Laboratory Medicine
13. Introduction to Laboratory Medicine
and Evidence-Based Laboratory Medicine 14. Selection and Analytical Evaluation of Methods?with Statistical Techniques 15. Clinical
Evaluation of Methods 16. Establishment and Use of Reference Values 17. Preanalytical Variables and Biological Variation 18.
Clinical Laboratory Informatics 19. Quality Management
Section 4 Analytes
20. Amino Acids, Peptides, and
Proteins 21. Enzymes 22. Cytokines 23. Tumor Markers 24. Kidney Function Tests 25. Carbohydrates 26. Lipids, Lipoproteins,
Apolipoproteins, and Other Cardiovascular Risk Factors 27. Electrolytes and Blood Gases 28. Hormones 29. Catecholamines and
Serotonin 30. Vitamins and Trace Elements 31. Hemoglobin, Iron, and Bilirubin 32. Porphyrins and Disorders of Porphyrin Metabolism 33.
Therapeutic Drugs and Their Management 34. Clinical Toxicology 35. Toxic Metals
Section 5 Molecular Diagnostics
and Genetics
36. Principles of Molecular Biology and Approaches to Nucleic Acid Isolation 37. Nucleic Acid Techniques 38.
Design and Operation of the Molecular Diagnostics Laboratory 39. Molecular Genetics and Diagnosis of Hematopoietic Neoplasms 40.
Inherited Diseases 41. Identity Assessment 42. Molecular Methods in Diagnosis and Monitoring of Infectious Diseases 43. Pharmacogenetics
Section
6 Pathophysiology
44. Cardiac Function 45. Kidney Disease 46. Physiology and Disorders of Water, Electrolyte, and
Acid-Base Metabolism 47. Liver Disease 48. Gastric, Pancreatic, and Intestinal Function 49. Mineral and Bone Metabolism 50.
Pituitary Function 51. The Adrenal Cortex 52. The Thyroid?Pathophysiology and Thyroid Function Testing 53. Reproductive Related
Disorders 54. Clinical Chemistry of Pregnancy 55. Inborn Errors of Amino Acid, Organic Acid, and Fatty Acid Metabolism
Section
7 Appendix
56. Reference Information for the Clinical Laboratory
| Bibliographic details |
Hardbound, 2448 pages, publication date: JUL-2005
ISBN-13: 978-0-7216-0189-2
ISBN-10: 0-7216-0189-8
Imprint: SAUNDERS
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026/235
Last update: 30 Nov 2009
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