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| AUTOMATION: GENOMIC AND FUNCTIONAL ANALYSES, 28
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Alister Craig, Liverpool School of Tropical Medicine, Liverpool, U.K.
J rg Hoheisel, Functional Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Included in series
Methods in Microbiology,
Description
Automation is the major future trend for many areas in microbiology, molecular biology and biochemistry, among other disciplines. It is
an enormously exciting area, where techniques and assays that were once repetitive, tedious and time consuming, can be performed robotically,
liberating the time of researchers and hospital laboratory workers for more interesting work. Many techniques have now been automated
and often miniaturized, including PCR analysis, DNA/RNA preparation, diagnostic tests (e.g., Pap tests), compound screening and, of course,
sequencing. Some major advances, notably in Professor Lee Hood's group, have resulted in the ability to perform thousands of assays simultaneously
on a normal microscope slide.Automation, edited by two of the leading experts in the field, presents the very latest
experimental techniques explained in detail. This book has succeeded in bringing together researchers at the forefront of clone library
construction, genome analysis, sequencing, computation data evaluation and functional analysis, to provide insight into this "new age"
of research based on genomic and chemical screening.
Audience
Molecular biologists, genetics, biochemists, cell biologists, pharmacologists, microscopists, microbiologist, and clinical researchers.
Contents
L. Hood, Foreword.U. Pettersson, Introduction.A. Fife and D.W.M. Crook, Automation in Clinical Microbiology.
A.J.McCollum, Vision Systems for Automated Colony and Plaque Picking.D.R. Bancroft, E. Maier and H. Lehrach, Library
Picking, Presentation and Analysis.G. Kauer and H. Blöcker, The PREPSEQ Robot: An Integrated Environment for Fully Automated
and Unattended Plasmid Preparations and Sequencing Reactions.A.N. Hale, Building Realistic Automated Production Lines for Genetic
Analysis.A.N. Hale, Examples of Automated Genetic Analysis Developments.L. Rowen, S. Lasky and L. Hood, Deciphering
Genomes Through Automated Large-scale Sequencing.N.C. Hauser, M. Scheideler, S. Matysiak, M. Vingron and J.D. Hoheisel, DNA
Arrays for Transcriptional Profiling.K.-J. Reiger, G. Orlowska, A. Kaniak, J.-Y. Coppee, G. Alijinovic and P.P. Slonimski,
Large-scale Phenotypic Analysis in Microtitre Plates of Mutants with Deleted Open Reading Frames From Yeast Chromosome III: Key-step
Between Genomic Sequencing And Protein Function.J.J. Codani, J.P. Comet, J.C. Aude, E. Glémet, A. Wozniak, J.L. Risler, A.
Hénaut and P.P. Slonimski, Automatic Analysis of Large-scale Pairwise Alignments of Protein Sequences.M.Y. Galperin and
D. Frishman, Towards Automated Prediction of Protein Function from Microbial Genomic Sequences.
Index.
| Bibliographic details |
Paperback, 270 pages, publication date: FEB-1999
ISBN-13: 978-0-12-194860-3
ISBN-10: 0-12-194860-9
Imprint: ACADEMIC PRESS
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| Price and Ordering |
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USD 81.95
GBP 39.95
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