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COMPREHENSIVE MEDICINAL CHEMISTRY II
Comprehensive Medicinal Chemistry II
Volume 7: THERAPEUTIC AREAS II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology
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Edited By
Jake Plattner, Anacor Pharmaceuticals Incorporated, Palo Alto, CA, USA
Manoj Desai, Gilead Sciences, Inc., Foster City, CA, USA

Description
This volume reviews important therapeutic areas, their causes, diagnosis, experimental disease models, treatments, unmet medical needs and future research areas. Areas covered include Cancer (biology, chemotherapy, mechanism & target approaches), Infectious Diseases (viral [herpes, HIV], fungal, bacterial & parasitic), Inflammation & Immunology (arthritis, asthma) and Dermatology (acne, psoriasis). For each area experts examine the key roles that medicinal chemistry and pharmacology play in reviving the fortunes of the drug discovery process and developing new treatments. Ideal for students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.

Audience


For students and researchers in chemistry, biochemistry, medicinal chemistry and pharmacology and scientists working in the pharmaceutical industries.



Contents


Volume 7 Therapeutic Areas II: Cancer, Infectious Diseases, Inflammation & Immunology and Dermatology


Anti Cancer

7.01 Cancer Biology
7.02 Principles of Chemotherapy and Pharmacology
7.03 Antimetabolites
7.04 Microtubule Targeting Agents
7.05 Deoxyribonucleic Acid Topoisomerase Inhibitors
7.06 Alkylating and Platinum Antitumor Compounds
7.07 Endocrine Modulating Agents
7.08 Kinase Inhibitors for Cancer
7.09 Recent Development in Novel Anticancer Therapies


Anti Viral

7.10 Viruses and Viral Diseases
7.11 Deoxyribonucleic Acid Viruses: Antivirals for Herpesviruses and Hepatitis B Virus
7.12 Ribonucleic Acid Viruses: Antivirals for Human Immunodeficiency Virus
7.13 Ribonucleic Acid Viruses: Antivirals for Influenza A and B, Hepatitis C Virus, and Respiratory Syncytial Virus


Anti Fungal

7.14 Fungi and Fungal Disease
7.15 Major Antifungal Drugs


Anti Bacterials

7.16 Bacteriology, Major Pathogens, and Diseases
7.17 ?-Lactam Antibiotics
7.18 Macrolide Antibiotics
7.19 Quinolone Antibacterial Agents
7.20 The Antibiotic and Nonantibiotic Tetracyclines
7.21 Aminoglycosides Antibiotics
7.22 Anti-Gram Positive Agents of Natural Product Origins
7.23 Oxazolidinone Antibiotics
7.24 Antimycobacterium Agents
7.25 Impact of Genomics-Emerging Targets for Antibacterial Therapy


Drugs for Parasitic Infections

7.26 Overview of Parasitic Infections
7.27 Advances in the Discovery of New Antimalarials
7.28 Antiprotozoal Agents (African Trypanosomiasis, Chagas Disease, and Leishmaniasis)


I and I Diseases

7.29 Recent Advances in Inflammatory and Immunological Diseases: Focus on Arthritis Therapy
7.30 Asthma and Chronic Obstructive Pulmonary Disease
7.31 Treatment of Transplantation Rejection and Multiple Sclerosis


Dermatology

7.32 Overview of Dermatological Diseases
7.33 Advances in the Discovery of Acne and Rosacea Treatments
7.34 New Treatments for Psoriasis and Atopic Dermatitis



Bibliographic details
Hardbound, 1060 pages, publication date: NOV-2006
ISBN-13: 978-0-08-044520-5
ISBN-10: 0-08-044520-9
Imprint: ELSEVIER

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USD 495
EUR 325
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Last update: 5 Sep 2009
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