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| CLINICAL UPDATE ON ADULT AND PEDIATRIC GASTROINTESTINAL STROMAL TUMOR, AN ISSUE OF HEMATOLOGY/ONCOLOGY CLINICS, 23-1
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By
Jonathan Trent, MD, PhD
Shreyaskumar Patel, MD
Included in series
The Clinics: Internal Medicine,
Description
Most doctors believe gastrointestinal stromal tumors (GISTs) start in special cells found in the wall of the GI tract, called the interstitial
cells of Cajal (ICCs), or in very early cells that can develop into ICCs. ICCs are part of the autonomic nervous system, which sends
signals to the GI tract. Some have called these cells the "pacemakers" of the GI tract because the nerve signals they send cause muscles
of the digestive organs to contract, which helps to move food and liquid through the GI tract. This issue is an important one because
GISTs are rare and are quite different in their outlook for survival and their treatment than other gastrointestinal tumors. For these
reasons, oncologists need to figure out whether a patient has a GIST, an adenoma, an adenocarcinoma, a neuroendocrine cancer, some other
type of tumor, or a non-cancerous condition. By presenting state-of-the-art information on the diagnosis, treatment, and management
of GISTs, this issue serves as an important guide to oncologists as they work with patients to make make informed decisions about treatment
options.
| Bibliographic details |
Hardbound, 240 pages, publication date: MAR-2009
ISBN-13: 978-1-4377-0486-0
ISBN-10: 1-4377-0486-7
Imprint: SAUNDERS
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041/407
Last update: 25 Nov 2009
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