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| SEROTONIN-DOPAMINE INTERACTION: EXPERIMENTAL EVIDENCE AND THERAPEUTIC RELEVANCE, 172
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Edited By
Giuseppe Di Giovanni, Dipartimento di Medicina Sperimentale, Sezione di Fisiologia Umana, G. Pagano , Universita` di Palermo, Italy
Vincenzo Di Matteo, Istituto di Ricerche Farmacologiche Mario Negri, Italy
Ennio Esposito, Istituto di Ricerche Farmacologiche Mario Negri, Italy
Included in series
Progress in Brain Research, 172
Description
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and
behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role
in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter
systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson?s disease. This extremely
important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners
and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological
states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently
active areas of dopamine/serotonin interactions.
Audience
Clinical Psychiatrists, Primary Care Physicians, and specialists in the behavioral health community. Also Graduate students and researchers
involved with serotonergic and dopaminergic systems. Possibly Pharmaceutical companies who market dopaminergic and serotonergic drugs
Contents
1. SEROTONIN-DOPAMINE INTERACTIONS IN THE CENTRAL NERVOUS SYSTEM
1. Serotonin-Dopamine Interaction: an overview
E. Esposito, V. Di Matteo
and G. Di Giovanni (Santa Maria Imbaro, Chieti and Palermo, Italy)
2. Serotonin control of central dopaminergic function: focus on in
vivo microdialysis studies
V. Di Matteo, G. Di Giovanni, M. Pierucci and E. Esposito (Santa Maria Imbaro, Chieti and Palermo, Italy)
3. Serotonin-Dopamine Interaction: electrophysiological evidence
G. Di Giovanni, V. Di Matteo, M. Pierucci and E. Esposito (Palermo
and Santa Maria Imbaro, Chieti, Italy
4. Functional genetic polymorphisms in serotonin and dopamine gene systems and their significance
in behavioural disorders
U.M. D?Souza and I.W. Craig (London, UK)
2. SEROTONIN-DOPAMINE INTERACTIONS IN SCHIZOPHRENIA
5. Distribution
of 5-HT and DA receptors in primate prefrontal cortex: implications for pathophysiology and treatment
J. de Almeida, J.M. Palacios and
G. Mengod (Barcelona, Spain)
6. Alterations of dopamine and serotonin transmission in schizophrenia
G. Remington (Toronto, ON, Canada)
7. Serotonin and dopamine interactions in psychosis prevention
N.M. Richtand and R.K. McNamara (Cincinnati, OH, USA)
8. Role of serotonin
and dopamine receptor binding in antipsychotic efficacy
N.M. Richtand, J.A. Welge, A.D. Logue, P.E. Keck, Jr., S.M. Strakowski and R.K.
McNamara (Cincinnati, OH, USA)
9. In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
H.Y. Meltzer
and M. Huang (Nashville, TN, USA)
10. Neuropharmacology of second-generation antipsychotic drugs: a validity of the serotonin-dopamine
hypothesis
T. Kuroki, N. Nagao and T. Nakahara (Kanzaki, Japan)
11. Serotonin-dopamine interactions: implications for the design of
novel therapeutic agents for psychiatric disorders
M.D. Wood and P.W. Wren (Harlow, UK)
3. SEROTONIN-DOPAMINE INTERACTIONS IN DEPRESSION
12. The dorsal raphe nucleus and serotonin ?implications for neuroplasticity linked to major depression and Alzheimer?s disease
K.A.
Michelsen, J. Prickaerts and H.W.M. Steinbusch (Maastricht, The Netherlands)
13. Dynamics of the dopaminergic system as a key component
to the understanding of depression
G. Yadid and A. Friedman (Ramat-Gan, Israel)
14. Physiological and therapeutic relevance of constitutive
activity of 5-HT2A and 5-HT2C receptors for the treatment of depression
K.A. Berg, J.A. Harvey, U. Spampinato and W.P. Clarke (San Antonio,
TX, Philadelphia, PA, USA and Bordeaux, France)
15. The role of dopamine and serotonin in suicidal behaviour and aggression
E. Ryding,
M. Lindstrom and L.Traskman-Bendz (Stockholm, Sweden)
4. SEROTONIN-DOPAMINE INTERACTIONS IN DRUG ADDICTION
16. Prospects for serotonin
5-HT2R pharmacotherapy in psychostimulant abuse
M.J. Bubar and K.A. Cunningham (Galveston, TX, USA)
17. Pharmacological inhibition
of dopamine- and serotonin activity blocks spontaneous and cocaine-activated behaviour
R.J. Carey, J.P. Huston and C.P. Muller (Dusseldorf,
Germany and London, UK)
18. Serotonin receptors as potential targets for modulation of nicotine use and dependence
P.J. Fletcher, A.
Dzung Le and G.A. Higgins (Toronto, ON, Canada)
19. Dopamine/Serotonin releasers as medications for stimulant addictions
R.B. Rothman,
B.E. Blough and M.H. Baumann (Baltimore, MD and Triangle Park, NC, USA)
20. PTEN-5-HT2C coupling: A new target for treating drug addiction
J.-C. Maillet, Y. Zhang, X. Li, X. Zhang (Ottawa, ON, Canada)
5. SEROTONIN-DOPAMINE INTERACTIONS IN MOTOR DISORDERS
21. Serotonin modulation
of the basal ganglia circuitry: therapeutic implication for Parkinson?s disease and other motor disorders
V. Di Matteo, M. Pierucci,
E. Esposito, G. Crescimanno, A. Benigno and G. Di Giovanni (Santa Maria Imbaro, Chieti, and Palermo, Italy)
22. Serotonin-Dopamine interaction
in the induction and maintenance of LDOPA-induced dyskinesias
M. Carta, T. Carlsson, A. Muňoz, D. Kirik and A. Bjorklund (Lund,
Sweden)
23. Parkinson?s disease – opportunities for novel therapeutics to reduce the problems of levodopa therapy
S.H. Fox, R. Chuang
and J.M. Brotchie (Toronto, ON, Canada)
24. Neurobiological basis of serotonin-dopamine antagonists in the treatment of Gilles de la
Tourette syndrome
| Bibliographic details |
Hardbound, 688 pages, publication date: SEP-2008
ISBN-13: 978-0-444-53235-0
Imprint: ELSEVIER
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095/945
Last update: 6 Nov 2009
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